Human immunodeficiency virus (HIV)

German Advisory Committee Blood … - Transfusion medicine …, 2016‏ - karger.com
German Advisory Committee Blood (Arbeitskreis Blut), Subgroup 'Assessment of Pathogens
Transmissible by Blood'tein, TM) are derived. In addition to the structural proteins, the HIV …

Diagnosis of human immunodeficiency virus infection

BS Parekh, CY Ou, PN Fonjungo… - Clinical microbiology …, 2018‏ - journals.asm.org
SUMMARY HIV diagnostics have played a central role in the remarkable progress in
identifying, staging, initiating, and monitoring infected individuals on life-saving antiretroviral …

Estimated HIV incidence in the United States, 2006–2009

J Prejean, R Song, A Hernandez, R Ziebell, T Green… - PloS one, 2011‏ - journals.plos.org
Background The estimated number of new HIV infections in the United States reflects the
leading edge of the epidemic. Previously, CDC estimated HIV incidence in the United States …

Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection

EW Fiebig, DJ Wright, BD Rawal, PE Garrett… - Aids, 2003‏ - journals.lww.com
Objectives: The characterization of primary HIV infection by the analysis of serial plasma
samples from newly infected persons using multiple standard viral assays. Design: A …

Generalizing evidence from randomized clinical trials to target populations: the ACTG 320 trial

SR Cole, EA Stuart - American journal of epidemiology, 2010‏ - academic.oup.com
Properly planned and conducted randomized clinical trials remain susceptible to a lack of
external validity. The authors illustrate a model-based method to standardize observed trial …

Primary HIV-1 Infection Is Associated with Preferential Depletion of CD4+ T Lymphocytes from Effector Sites in the Gastrointestinal Tract

S Mehandru, MA Poles, K Tenner-Racz… - The Journal of …, 2004‏ - rupress.org
Given its population of CCR5-expressing, immunologically activated CD4+ T cells, the
gastrointestinal (GI) mucosa is uniquely susceptible to human immunodeficiency virus (HIV) …

Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size

V Jain, W Hartogensis, P Bacchetti… - The Journal of …, 2013‏ - academic.oup.com
Abstract Background. CD4+/CD8+ T-cell activation levels often remain elevated in chronic
human immunodeficiency virus (HIV) infection despite initiation of antiretroviral therapy …

Estimation of HIV incidence in the United States

HI Hall, R Song, P Rhodes, J Prejean, Q An, LM Lee… - Jama, 2008‏ - jamanetwork.com
Context Incidence of human immunodeficiency virus (HIV) in the United States has not been
directly measured. New assays that differentiate recent vs long-standing HIV infections allow …

Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load

SG Deeks, CMR Kitchen, L Liu, H Guo, R Gascon… - Blood, 2004‏ - ashpublications.org
Although generalized T-cell activation is an important factor in chronic HIV disease
pathogenesis, its role in primary infection remains poorly defined. To investigate the effect of …

Antiretroviral-drug resistance among patients recently infected with HIV

SJ Little, S Holte, JP Routy, ES Daar… - … England Journal of …, 2002‏ - Mass Medical Soc
Background Among persons in North America who are newly infected with the human
immunodeficiency virus (HIV), the prevalence of transmitted resistance to antiretroviral drugs …