High-depth African genomes inform human migration and health
The African continent is regarded as the cradle of modern humans and African genomes
contain more genetic variation than those from any other continent, yet only a fraction of the …
contain more genetic variation than those from any other continent, yet only a fraction of the …
Inferring population structure and admixture proportions in low-depth NGS data
Meisner and Albrechtsen present two methods for inferring population structure and
admixture proportions in low depth next-generation sequencing (NGS). NGS methods …
admixture proportions in low depth next-generation sequencing (NGS). NGS methods …
Origins and genetic legacy of Neolithic farmers and hunter-gatherers in Europe
The farming way of life originated in the Near East some 11,000 years ago and had reached
most of the European continent 5000 years later. However, the impact of the agricultural …
most of the European continent 5000 years later. However, the impact of the agricultural …
[HTML][HTML] Genomic patterns of homozygosity in worldwide human populations
TJ Pemberton, D Absher, MW Feldman… - The American Journal of …, 2012 - cell.com
Genome-wide patterns of homozygosity runs and their variation across individuals provide a
valuable and often untapped resource for studying human genetic diversity and evolutionary …
valuable and often untapped resource for studying human genetic diversity and evolutionary …
[HTML][HTML] Recent advances in the study of fine-scale population structure in humans
Empowered by modern genoty** and large samples, population structure can be
accurately described and quantified even when it only explains a fraction of a percent of total …
accurately described and quantified even when it only explains a fraction of a percent of total …
Ancient genomes link early farmers from Atapuerca in Spain to modern-day Basques
The consequences of the Neolithic transition in Europe—one of the most important cultural
changes in human prehistory—is a subject of great interest. However, its effect on prehistoric …
changes in human prehistory—is a subject of great interest. However, its effect on prehistoric …
A genomic history of Aboriginal Australia
The population history of Aboriginal Australians remains largely uncharacterized. Here we
generate high-coverage genomes for 83 Aboriginal Australians (speakers of Pama …
generate high-coverage genomes for 83 Aboriginal Australians (speakers of Pama …
Genomic variation in seven Khoe-San groups reveals adaptation and complex African history
The history of click-speaking Khoe-San, and African populations in general, remains poorly
understood. We genotyped∼ 2.3 million single-nucleotide polymorphisms in 220 southern …
understood. We genotyped∼ 2.3 million single-nucleotide polymorphisms in 220 southern …
PACo: a novel procrustes application to cophylogenetic analysis
We present Procrustean Approach to Cophylogeny (PACo), a novel statistical tool to test for
congruence between phylogenetic trees, or between phylogenetic distance matrices of …
congruence between phylogenetic trees, or between phylogenetic distance matrices of …
Perspectives on human population structure at the cusp of the sequencing era
Human groups show structured levels of genetic similarity as a consequence of factors such
as geographical subdivision and genetic drift. Surveying this structure gives us a scientific …
as geographical subdivision and genetic drift. Surveying this structure gives us a scientific …