The cation− π interaction is an attractive noncovalent interaction between a cation and a π
system. Due to the stronger interaction energy than those of the other π interactions, such as …

Abstract C (1)‐Ammonium enolates are powerful, catalytically generated synthetic
intermediates applied in the enantioselective α‐functionalisation of carboxylic acid …

Abstract The importance of 1, 5‐O⋅⋅⋅ chalcogen (Ch) interactions in isochalcogenourea
catalysis (Ch= O, S, Se) is investigated. Conformational analyses of N‐acyl …

An enantioselective [4+ 3] cyclization via C (sp2)–H activation with a cooperative catalytic
system consisting of a Cp* Rh (III) complex and a chiral Lewis base is described. An α, β …

A protocol for the enantioselective synthesis of substituted vinylcyclopentanes has been
realised using cooperative palladium and isothiourea catalysis. Treatment of …

Chemistry in continuous-flow continues to attract attention from the community of synthetic
organic chemists due to its now well-recognized benefits including, inter alia, quick reaction …

The first highly enantioselective CuI‐catalyzed azide‐alkyne cycloaddition (CuAAC) of
tertiary alcohols and their kinetic resolution is reported. This approach allows facile access …

Chiral γ-lactam-containing skeletons are important motifs in bioactive natural products,
pharmaceuticals, and bioactive molecules. Herein, we report a general and modular …

α, β-Unsaturated acyl ammonium species are versatile intermediates that have been applied
in a variety of transformations including Michael additions, domino reactions and …

In this work we describe the synthesis of potent and selective quinolone-based histone
deacetylase 6 (HDAC6) inhibitors. The quinolone moiety has been exploited as an …