Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39
K Devantier, VMS Kjær, S Griffin… - British Journal of …, 2024 - Wiley Online Library
Viroporins possess important potential as antiviral targets due to their critical roles during
virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine …
virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine …
The cytoplasmic domain of the SARS-CoV-2 envelope protein assembles into a β-sheet bundle in lipid bilayers
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein
forms a pentameric ion channel in the lipid membrane of the endoplasmic reticulum Golgi …
forms a pentameric ion channel in the lipid membrane of the endoplasmic reticulum Golgi …
SARS-CoV-2 envelope protein alters calcium signaling via SERCA interactions
The clinical management of severe COVID-19 cases is not yet well resolved. Therefore, it is
important to identify and characterize cell signaling pathways involved in virus pathogenesis …
important to identify and characterize cell signaling pathways involved in virus pathogenesis …
Develo** inhibitory peptides against SARS-CoV-2 envelope protein
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has affected
approximately 800 million people since the start of the Coronavirus Disease 2019 (COVID …
approximately 800 million people since the start of the Coronavirus Disease 2019 (COVID …
Distinguishing Different Hydrogen-Bonded Helices in Proteins by Efficient 1H-Detected Three-Dimensional Solid-State NMR
Helical structures in proteins include not only α-helices but also 310 and π helices. These
secondary structures differ in the registry of the C═ O··· H–N hydrogen bonds, which are i to …
secondary structures differ in the registry of the C═ O··· H–N hydrogen bonds, which are i to …
Transmembrane conformation of the envelope protein of an alpha coronavirus, NL63
The envelope (E) proteins of coronaviruses (CoVs) form cation‐conducting channels that
are associated with the pathogenicity of these viruses. To date, high‐resolution structural …
are associated with the pathogenicity of these viruses. To date, high‐resolution structural …
[HTML][HTML] Prediction of conformational states in a coronavirus channel using Alphafold-2 and DeepMSA2: Strengths and limitations
The envelope (E) protein is present in all coronavirus genera. This protein can form
pentameric oligomers with ion channel activity which have been proposed as a possible …
pentameric oligomers with ion channel activity which have been proposed as a possible …
The Complex Proteolipidic Behavior of the SARS-CoV-2 Envelope Protein Channel: Weak Selectivity and Heterogeneous Oligomerization
W Surya, E Tavares-Neto, A Sanchis… - International Journal of …, 2023 - mdpi.com
The envelope (E) protein is a small polypeptide that can form ion channels in coronaviruses.
In SARS coronavirus 2 (SARS-CoV-2), the agent that caused the recent COVID-19 …
In SARS coronavirus 2 (SARS-CoV-2), the agent that caused the recent COVID-19 …