Interactions between the nervous and immune systems enable the gut to respond to the
variety of dietary products that it absorbs, the broad spectrum of pathogens that it …

IgE-dependent mast cell activation is a major effector mechanism underlying the pathology
associated with allergic disorders. The most dramatic of these IgE-associated disorders is …

Although IL-4 induces expulsion of the gastrointestinal nematode parasite, Nippostrongylus
brasiliensis, from immunodeficient mice, this parasite is expelled normally by IL-4-deficient …

▪ Abstract Studies with rodents infected with Trichinella spiralis, Heligmosomoides
polygyrus, Nippostrongylus brasiliensis, and Trichuris muris have provided considerable …

The Biology of Nematodes synthesizes literature on free-living, plant-parasitic, and animal-
parasitic nematodes. Topics covered include systematics and phylogeny, neuromuscular …

Strongyloides stercoralis is the most common human parasitic nematode that is able to
complete a life cycle and proliferate within its host. The majority of patients with …

Isolated cases and outbreaks of infection with Trichinella spp. occur frequently throughout
the world, sometimes resulting in fatalities. The clinical presentations of signs and symptoms …

Studies with murine models demonstrate 2 pathways of systemic anaphylaxis: one mediated
by IgE, FcεRI, mast cells, histamine, and platelet-activating factor (PAF), and the other …

Trichinella spiralis infection elicits a vigorous IgE response and pronounced intestinal and
splenic mastocytosis in mice. Since IgE both activates mast cells (MC) and promotes their …

Laboratory models of intestinal nematode infection have played an important role in
develo** our understanding of the immune mechanisms that operate against infectious …