Multiscale lipid membrane dynamics as revealed by neutron spectroscopy

VK Sharma, E Mamontov - Progress in Lipid Research, 2022 - Elsevier
The plasma membrane is one of the principal structural components of the cell and,
therefore, one of the key components of the cellular life. Because the membrane's dynamics …

High-resolution neutron spectroscopy using backscattering and neutron spin-echo spectrometers in soft and hard condensed matter

JS Gardner, G Ehlers, A Faraone… - Nature Reviews …, 2020 - nature.com
The instruments best suited to performing high-energy-resolution neutron spectroscopy are
spin-echo spectrometers and backscattering spectrometers. The development of these …

[HTML][HTML] Imidazolium-based ionic liquids cause mammalian cell death due to modulated structures and dynamics of cellular membrane

K Bakshi, S Mitra, VK Sharma, MSK Jayadev… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Here, we report the toxic effects of various imidazolium-based ionic liquids (ILs) with varying
hydrocarbon chain lengths, on different human cell lines. Multiple biological assays have …

Understanding the structure and dynamics of complex biomembrane interactions by neutron scattering techniques

S Qian, VK Sharma, LA Clifton - Langmuir, 2020 - ACS Publications
The membrane is one of the key structural materials of biology at the cellular level.
Composed predominantly of a bilayer of lipids with embedded and bound proteins, it defines …

Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance

HX Luong, HD Ngan… - Royal Society …, 2022 - royalsocietypublishing.org
In the last century, conventional antibiotics have played a significant role in global
healthcare. Antibiotics support the body in controlling bacterial infection and simultaneously …

Effects of ionic liquids on biomembranes: A review on recent biophysical studies

S Mitra, VK Sharma, SK Ghosh - Chemistry and Physics of Lipids, 2023 - Elsevier
Ionic liquids (ILs) have been emerged as a versatile class of compounds that can be easily
tuned to achieve desirable properties for various applications. The ability of ILs to interact …

Lipid lateral diffusion: mechanisms and modulators

VK Sharma, H Srinivasan, J Gupta, S Mitra - Soft Matter, 2024 - pubs.rsc.org
The lateral diffusion of lipids within membrane is of paramount importance, serving as a
central mechanism in numerous physiological processes including cell signaling …

Backscattering silicon spectrometer (BASIS): sixteen years in advanced materials characterization

NC Osti, N Jalarvo, E Mamontov - Materials Horizons, 2024 - pubs.rsc.org
Quasielastic neutron scattering (QENS) is an experimental technique that can measure
parameters of mobility, such as diffusion jump rate and jump length, as well as localized …

Effects of ionic liquids on the nanoscopic dynamics and phase behaviour of a phosphatidylcholine membrane

VK Sharma, SK Ghosh, P Mandal, T Yamada… - Soft Matter, 2017 - pubs.rsc.org
Ionic liquids (ILs) are potential candidates for new antimicrobials due to their tunable
antibacterial and antifungal properties that are required to keep pace with the growing …

Dynamics of liposomes in the fluid phase

S Gupta, JU De Mel, GJ Schneider - Current Opinion in Colloid & Interface …, 2019 - Elsevier
We review the currently available material on the morphology and dynamics of
phospholipids assembled into liposomes. Key information obtained from neutron scattering …