The identification and characterization of cis-regulatory DNA sequences and how they
function to coordinate responses to developmental and environmental cues is of paramount …

Coloration is an easily quantifiable visual trait that has proven to be a highly tractable system
for genetic analysis and for studying adaptive evolution. The application of genomic …

The rediscovery of Mendel's work showing that the heredity of phenotypes is controlled by
discrete genes was followed by the reconciliation of Mendelian genetics with evolution by …

Butterfly wing patterns derive from a deeply conserved developmental ground plan yet are
diverse and evolve rapidly. It is poorly understood how gene regulatory architectures can …

Many organisms exhibit visually striking spotted or striped pigmentation patterns.
Developmental models predict that such spatial patterns can form when a local autocatalytic …

Butterfly eyespots are beautiful novel traits with an unknown developmental origin. Here we
show that eyespots likely originated via cooption of parts of an ancestral appendage gene …

Long noncoding RNAs (lncRNAs) are transcribed elements increasingly recognized for their
roles in regulating gene expression. Thus far, however, we have little understanding of how …

Epigenetic mechanisms such as DNA methylation, histone modifications and non-coding
RNAs are increasingly targeted in studies of natural populations. Here, I review some of the …

Little is known about the extent to which species use homologous regulatory architectures to
achieve phenotypic convergence. By characterizing chromatin accessibility and gene …

Genetic variation segregates as linked sets of variants or haplotypes. Haplotypes and
linkage are central to genetics and underpin virtually all genetic and selection analysis. Yet …