[HTML][HTML] Application of next generation sequencing in laboratory medicine
The rapid development of next-generation sequencing (NGS) technology, including
advances in sequencing chemistry, sequencing technologies, bioinformatics, and data …
advances in sequencing chemistry, sequencing technologies, bioinformatics, and data …
[HTML][HTML] Conserved pan-cancer microenvironment subtypes predict response to immunotherapy
The clinical use of molecular targeted therapy is rapidly evolving but has primarily focused
on genomic alterations. Transcriptomic analysis offers an opportunity to dissect the …
on genomic alterations. Transcriptomic analysis offers an opportunity to dissect the …
Liquid biopsy in bladder cancer: State of the art and future perspectives
Bladder cancer is the most common malignancy of the urinary tract. Cystoscopy represents
the gold standard in the diagnosis of suspicious bladder lesions. However, the procedure is …
the gold standard in the diagnosis of suspicious bladder lesions. However, the procedure is …
Benefits for children with suspected cancer from routine whole-genome sequencing
A Hodder, SM Leiter, J Kennedy, D Addy, M Ahmed… - Nature Medicine, 2024 - nature.com
Clinical whole-genome sequencing (WGS) has been shown to deliver potential benefits to
children with cancer and to alter treatment in high-risk patient groups. It remains unknown …
children with cancer and to alter treatment in high-risk patient groups. It remains unknown …
Clinical genomics for the diagnosis of monogenic forms of inflammatory bowel disease: a position paper from the Paediatric IBD Porto Group of European Society of …
HH Uhlig, F Charbit-Henrion, D Kotlarz… - Journal of pediatric …, 2021 - journals.lww.com
Background: It is important to identify patients with monogenic IBD as management may
differ from classical IBD. In this position statement we formulate recommendations for the …
differ from classical IBD. In this position statement we formulate recommendations for the …
Implementation of whole-genome and transcriptome sequencing into clinical cancer care
PURPOSE The combination of whole-genome and transcriptome sequencing (WGTS) is
expected to transform diagnosis and treatment for patients with cancer. WGTS is a …
expected to transform diagnosis and treatment for patients with cancer. WGTS is a …
Next-generation sequencing in newborn screening: a review of current state
ZI Remec, K Trebusak Podkrajsek… - Frontiers in …, 2021 - frontiersin.org
Newborn screening was first introduced at the beginning of the 1960s with the successful
implementation of the first phenylketonuria screening programs. Early expansion of the …
implementation of the first phenylketonuria screening programs. Early expansion of the …
Robotics, microfluidics, nanotechnology and AI in the synthesis and evaluation of liposomes and polymeric drug delivery systems
E Egorov, C Pieters, H Korach-Rechtman… - Drug Delivery and …, 2021 - Springer
The field of nanotechnology and personalised medicine is undergoing drastic changes in
the approach and efficiency of experimentation. The COVID-19 pandemic has spiralled into …
the approach and efficiency of experimentation. The COVID-19 pandemic has spiralled into …
[HTML][HTML] Metagenomics and artificial intelligence in the context of human health
Human microbiome is ubiquitous, dynamic, and site-specific consortia of microbial
communities. The pathogenic nature of microorganisms within human tissues has led to an …
communities. The pathogenic nature of microorganisms within human tissues has led to an …
Unlocking the efficiency of genomics laboratories with robotic liquid-handling
In research and clinical genomics laboratories today, sample preparation is the bottleneck of
experiments, particularly when it comes to high-throughput next generation sequencing …
experiments, particularly when it comes to high-throughput next generation sequencing …