Bruce F. Waller, MD; Cass A. Pinkerton, MD; and John D. Slack, MD uring the last several
years, dramatic develop-D ments have taken place in the area of cardiac imaging …

Abstract Aims Homozygous familial hypercholesterolaemia (HoFH) is an orphan disease
defined by extreme elevations in low-density lipoprotein cholesterol, cutaneous xanthomas …

The third edition of this well-received text provides a state-of-the-art treatise on modern
clinical practice relating to hyperlipidaemia and lipoprotein disorders, conditions responsible …

Background—In homozygous familial hypercholesterolemia (HFH), the aortic root is prone to
develop atherosclerotic plaque at an early age. However, the aortic wall and plaque have …

In some individuals, a high cholesterol concentration in the blood is caused by an inherited
genetic defect known as familial hypercholesterolaemia (FH). Raised cholesterol …

Objective To compare the frequency of valvar and supravalvar aortic stenosis in
homozygous and heterozygous familial hypercholesterolaemia (FH). Design Analysis of life …

Long-term data on the effects of cholesterol-lowering regimens on low-density lipoprotein
cholesterol levels and cardiovascular events in patients with familial hypercholesterolemia …

Background Homozygous familial hypercholesterolemia (HoFH) is a rare, life-threatening
inherited disease leading to early-onset atherosclerosis and associated morbidity. Because …

Isolated coronary ostial stenosis is a rare condition of unknown etiology previously reported
in only 22 patients. Of 2,105 consecutive patients with angiographically defined coronary …

Small rodents, especially mice and rats, have been widely used in atherosclerosis studies
even though humans exhibit completely different lipoprotein metabolism and atherosclerotic …