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Microbiome-based therapeutics
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
[HTML][HTML] The spread of antibiotic resistance to humans and potential protection strategies
D Ding, B Wang, X Zhang, J Zhang, H Zhang… - Ecotoxicology and …, 2023 - Elsevier
Antibiotic resistance is currently one of the greatest threats to human health. Widespread
use and residues of antibiotics in humans, animals, and the environment can exert selective …
use and residues of antibiotics in humans, animals, and the environment can exert selective …
Microbiome diversity protects against pathogens by nutrient blocking
The human gut microbiome plays an important role in resisting colonization of the host by
pathogens, but we lack the ability to predict which communities will be protective. We …
pathogens, but we lack the ability to predict which communities will be protective. We …
[HTML][HTML] Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites
D Bogaert, GJ Van Beveren, EM de Koff, PL Parga… - Cell Host & Microbe, 2023 - cell.com
Early-life microbiota seeding and subsequent development is crucial to future health.
Cesarean-section (CS) birth, as opposed to vaginal delivery, affects early mother-to-infant …
Cesarean-section (CS) birth, as opposed to vaginal delivery, affects early mother-to-infant …
[HTML][HTML] Microbiome-based interventions to modulate gut ecology and the immune system
The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …
Commensal consortia decolonize Enterobacteriaceae via ecological control
Persistent colonization and outgrowth of potentially pathogenic organisms in the intestine
can result from long-term antibiotic use or inflammatory conditions, and may perpetuate …
can result from long-term antibiotic use or inflammatory conditions, and may perpetuate …
Klebsiella oxytoca inhibits Salmonella infection through multiple microbiota-context-dependent mechanisms
The Klebsiella oxytoca species complex is part of the human microbiome, especially during
infancy and childhood. K. oxytoca species complex strains can produce enterotoxins …
infancy and childhood. K. oxytoca species complex strains can produce enterotoxins …
Salmonella Typhimurium expansion in the inflamed murine gut is dependent on aspartate derived from ROS-mediated microbiota lysis
W Yoo, NG Shealy, JK Zieba, TP Torres, M Baltagulov… - Cell host & …, 2024 - cell.com
Inflammation boosts the availability of electron acceptors in the intestinal lumen, creating a
favorable niche for pathogenic Enterobacteriaceae. However, the mechanisms linking …
favorable niche for pathogenic Enterobacteriaceae. However, the mechanisms linking …
Intestinal colonization resistance in the context of environmental, host, and microbial determinants
Microbial communities that colonize the human gastrointestinal (GI) tract defend against
pathogens through a mechanism known as colonization resistance (CR). Advances in …
pathogens through a mechanism known as colonization resistance (CR). Advances in …
Intrahost evolution of the gut microbiota
A massive number of microorganisms, belonging to different species, continuously divide
inside the guts of animals and humans. The large size of these communities and their rapid …
inside the guts of animals and humans. The large size of these communities and their rapid …