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Understanding key mechanisms of exercise-induced cardiac protection to mitigate disease: current knowledge and emerging concepts
The benefits of exercise on the heart are well recognized, and clinical studies have
demonstrated that exercise is an intervention that can improve cardiac function in heart …
demonstrated that exercise is an intervention that can improve cardiac function in heart …
The role of long non-coding RNA GAS5 in cancers
J Ji, X Dai, SCJ Yeung, X He - Cancer management and research, 2019 - Taylor & Francis
Long non-coding RNAs (lncRNAs) have shown potential as a biomarker in the diagnosis
and prognosis in multiple cancers. LncRNAs are dysregulated in various cancers, playing …
and prognosis in multiple cancers. LncRNAs are dysregulated in various cancers, playing …
'Multimorbidity'as the manifestation of network disturbances
We argue that 'multimorbidity'is the manifestation of interconnected physiological network
processes within an individual in his or her socio‐cultural environment. Networks include …
processes within an individual in his or her socio‐cultural environment. Networks include …
Health and disease—emergent states resulting from adaptive social and biological network interactions
Health is an adaptive state unique to each person. This subjective state must be
distinguished from the objective state of disease. The experience of health and illness (or …
distinguished from the objective state of disease. The experience of health and illness (or …
β-Arrestin based receptor signaling paradigms: Potential therapeutic targets for complex age-related disorders
J Van Gastel, JO Hendrickx, H Leysen… - Frontiers in …, 2018 - frontiersin.org
G protein coupled receptors (GPCRs) were first characterized as signal transducers that
elicit downstream effects through modulation of guanine (G) nucleotide-binding proteins …
elicit downstream effects through modulation of guanine (G) nucleotide-binding proteins …
The fractal heart—embracing mathematics in the cardiology clinic
For clinicians grappling with quantifying the complex spatial and temporal patterns of
cardiac structure and function (such as myocardial trabeculae, coronary microvascular …
cardiac structure and function (such as myocardial trabeculae, coronary microvascular …
Biopsychosocial approach to understanding resilience: Stress habituation and where to intervene
Background Resilience in the face of adversity is a human experience that leads to better
health, both mentally and physically. We briefly review its historical origins rooted in …
health, both mentally and physically. We briefly review its historical origins rooted in …
Comprehensive viewpoints on heart rate variability at high altitude
J Hou, K Lu, P Chen, P Wang, J Li, J Yang… - Clinical and …, 2023 - Taylor & Francis
Objectives Hypoxia is a physiological state characterized by reduced oxygen levels in
organs and tissues. It is a common clinicopathological process and a major cause of health …
organs and tissues. It is a common clinicopathological process and a major cause of health …
24-h continuous non-invasive multiparameter home monitoring of vitals in patients with Rett syndrome by an innovative wearable technology: evidence of an …
S Leoncini, L Boasiako, S Di Lucia, A Beker… - Frontiers in …, 2024 - frontiersin.org
Background Sleep is disturbed in Rett syndrome (RTT), a rare and progressive
neurodevelopmental disorder primarily affecting female patients (prevalence 7.1/100,000 …
neurodevelopmental disorder primarily affecting female patients (prevalence 7.1/100,000 …
Evidence‐based medicine—Not a panacea for the problems of a complex adaptive world
JP Sturmberg - Journal of evaluation in clinical practice, 2019 - Wiley Online Library
The recent sacking of Peter Gøtzsche from the Cochrane Collaboration Board raised strong
responses and highlights the neglected issue about priorities—maintaining the reputation of …
responses and highlights the neglected issue about priorities—maintaining the reputation of …