Seizure prediction—ready for a new era

L Kuhlmann, K Lehnertz, MP Richardson… - Nature Reviews …, 2018 - nature.com
Epilepsy is a common disorder characterized by recurrent seizures. An overwhelming
majority of people with epilepsy regard the unpredictability of seizures as a major issue …

Synchronization and desynchronization in epilepsy: controversies and hypotheses

P Jiruska, M De Curtis, JGR Jefferys… - The Journal of …, 2013 - Wiley Online Library
Epilepsy has been historically seen as a functional brain disorder associated with excessive
synchronization of large neuronal populations leading to a hypersynchronous state. Recent …

Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy

AN Khambhati, A Shafi, VR Rao… - Science Translational …, 2021 - science.org
Responsive neurostimulation (RNS) devices, able to detect imminent seizures and to rapidly
deliver electrical stimulation to the brain, are effective in reducing seizures in some patients …

Epilepsy as a disorder of cortical network organization

MA Kramer, SS Cash - The Neuroscientist, 2012 - journals.sagepub.com
The brain is naturally considered as a network of interacting elements which, when
functioning properly, produces an enormous range of dynamic, adaptable behavior …

Altered functional–structural coupling of large-scale brain networks in idiopathic generalized epilepsy

Z Zhang, W Liao, H Chen, D Mantini, JR Ding, Q Xu… - Brain, 2011 - academic.oup.com
The human brain is a large-scale integrated network in the functional and structural domain.
Graph theoretical analysis provides a novel framework for analysing such complex …

Human brain networks in health and disease

DS Bassett, ET Bullmore - Current opinion in neurology, 2009 - journals.lww.com
Graph theoretical analysis of neuroimaging data is growing rapidly and could potentially
provide a relatively simple but powerful quantitative framework to describe and compare …

[HTML][HTML] Epileptic-network-based prediction and control of seizures in humans

K Lehnertz, T Bröhl, R von Wrede - Neurobiology of disease, 2023 - Elsevier
Epilepsy is now conceptualized as a network disease. The epileptic brain network
comprises structurally and functionally connected cortical and subcortical brain regions …

Interchange of entire communities: microbial community coalescence

MC Rillig, J Antonovics, T Caruso, A Lehmann… - Trends in Ecology & …, 2015 - cell.com
Microbial communities are enigmatically diverse. We propose a novel view of processes
likely affecting microbial assemblages, which could be viewed as the Great American …

Functional and structural brain networks in epilepsy: what have we learned?

E van Diessen, SJH Diederen, KPJ Braun… - …, 2013 - Wiley Online Library
Brain functioning is increasingly seen as a complex interplay of dynamic neural systems that
rely on the integrity of structural and functional networks. Recent studies that have …

Network dynamics of the brain and influence of the epileptic seizure onset zone

SP Burns, S Santaniello, RB Yaffe, CC Jouny… - Proceedings of the …, 2014 - pnas.org
The human brain is a dynamic networked system. Patients with partial epileptic seizures
have focal regions that periodically diverge from normal brain network dynamics during …