[HTML][HTML] The role of infection and inflammation in the pathogenesis of pediatric arterial ischemic stroke

MC Cornet, C Grose, Z Vexler, YW Wu… - Seminars in pediatric …, 2022 - Elsevier
Infections play an important role in the pathogenesis of acute ischemic stroke (AIS) in
neonates and children. In neonates, chorioamnionitis or intrauterine inflammation has been …

Developmental priming of early cerebrovascular ageing: Implications across a lifetime

HB Stolp, E Solito - International journal of geriatric psychiatry, 2024 - Wiley Online Library
Introduction Neurological conditions such as Alzheimer's disease and stroke represent a
substantial health burden to the world's ageing population. Cerebrovascular dysfunction is a …

Brain maturation as a fundamental factor in immune-neurovascular interactions in stroke

E Di Martino, A Rayasam, ZS Vexler - Translational Stroke Research, 2024 - Springer
Injuries in the develo** brain cause significant long-term neurological deficits. Emerging
clinical and preclinical data have demonstrated that the pathophysiology of neonatal and …

Effect and safety of sivelestat on acute severe pancreatitis with systemic inflammatory response syndrome: a retrospective study

J **e, R Lei, H Pei, Y Gu, L Zhang, J Liu, Y Huang… - Scientific Reports, 2025 - nature.com
The study was to explore the efficacy and safety of sivelestat (SV) in the treatment of severe
acute pancreatitis (SAP) with systemic inflammatory response syndrome (SIRS). A total of …

Vascular topology and blood flow are acutely impacted by experimental febrile status epilepticus

A Salehi, S Salari, A Jullienne… - Journal of Cerebral …, 2023 - journals.sagepub.com
Febrile status epilepticus (FSE) is an important risk factor for temporal lobe epilepsy and
early identification of those at high risk for epilepsy is vital. In a rat model of FSE, we …

Pre‐and post‐conditioning with poly I: C exerts neuroprotective effect against cerebral ischemia injury in animal models: A systematic review and meta‐analysis

ZA Khan, DM Sumsuzzman, J Choi… - CNS Neuroscience …, 2022 - Wiley Online Library
Background Toll‐like receptor (TLR) agonist polyinosinic–polycytidylic acid (poly I: C) exerts
neuroprotective effects against cerebral ischemia (CI), but concrete evidence supporting its …

Immune-Neurovascular Interactions in Experimental Perinatal and Childhood Arterial Ischemic Stroke

C Mallard, DM Ferriero, ZS Vexler - Stroke, 2024 - ahajournals.org
Emerging clinical and preclinical data have demonstrated that the pathophysiology of
arterial ischemic stroke in the adult, neonates, and children share similar mechanisms that …

Soluble lectin‐like oxidized low‐density Lipoproteinreceptor‐1 and recurrent stroke: A nested case–control study

A Wang, X Tian, J Xu, H Li, Q Xu… - CNS Neuroscience …, 2022 - Wiley Online Library
Main problem The prognostic value of soluble lectin‐like oxidized low‐density
lipoproteinreceptor‐1 (sLOX‐1) for stroke was unclearly. This study aimed to investigate the …

Could neutrophil extracellular traps drive the development of autism?

M Pastorek, D Drobna, P Celec - Medical Hypotheses, 2022 - Elsevier
Etiology of autism spectrum disorders (ASD) is as enigmatic as it is complex. Linking
genetic, hormonal and environmental factors, several studies proposed a multi-hit model …