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[HTML][HTML] GABAergic dysfunction, neural network hyperactivity and memory impairments in human aging and Alzheimer's disease
J Jiménez-Balado, TS Eich - Seminars in cell & developmental biology, 2021 - Elsevier
In this review, we focus on the potential role of the γ-aminobutyric acidergic (GABAergic)
system in age-related episodic memory impairments in humans, with a particular focus on …
system in age-related episodic memory impairments in humans, with a particular focus on …
A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra
CD Rae - Neurochemical research, 2014 - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …
resonances in human brain proton magnetic resonance spectra measureable at readily …
Impact of aging on the auditory system and related cognitive functions: a narrative review
Age-related hearing loss (ARHL), presbycusis, is a chronic health condition that affects
approximately one-third of the world's population. The peripheral and central hearing …
approximately one-third of the world's population. The peripheral and central hearing …
Not all brains are created equal: the relevance of individual differences in responsiveness to transcranial electrical stimulation
B Krause, R Cohen Kadosh - Frontiers in systems neuroscience, 2014 - frontiersin.org
A current issue in the research of augmentation of brain functions using transcranial
electrical stimulation (tES) is the diversity and inconsistency in outcome results. Similar …
electrical stimulation (tES) is the diversity and inconsistency in outcome results. Similar …
Alzheimer's disease: targeting the glutamatergic system
ME Conway - Biogerontology, 2020 - Springer
Alzheimer's disease (AD) is a debilitating neurodegenerative disease that causes a
progressive decline in memory, language and problem solving. For decades mechanism …
progressive decline in memory, language and problem solving. For decades mechanism …
Functional MRS studies of GABA and glutamate/Glx–A systematic review and meta-analysis
Functional magnetic resonance spectroscopy (fMRS) can be used to investigate
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …
Frontal gamma-aminobutyric acid concentrations are associated with cognitive performance in older adults
Background Gamma-aminobutyric acid (GABA), the brain's principal inhibitory
neurotransmitter, has been associated with perceptual and attentional functioning. Recent …
neurotransmitter, has been associated with perceptual and attentional functioning. Recent …
Edited 1H magnetic resonance spectroscopy in vivo: Methods and metabolites
The Proton magnetic resonance (1H‐MRS) spectrum contains information about the
concentration of tissue metabolites within a predefined region of interest (a voxel). The …
concentration of tissue metabolites within a predefined region of interest (a voxel). The …
Anxious individuals shift emotion control from lateral frontal pole to dorsolateral prefrontal cortex
Anxious individuals consistently fail in controlling emotional behavior, leading to excessive
avoidance, a trait that prevents learning through exposure. Although the origin of this failure …
avoidance, a trait that prevents learning through exposure. Although the origin of this failure …
Sensorimotor network segregation declines with age and is linked to GABA and to sensorimotor performance
Aging is typically associated with declines in sensorimotor performance. Previous studies
have linked some age-related behavioral declines to reductions in network segregation. For …
have linked some age-related behavioral declines to reductions in network segregation. For …