Innovative treatment strategies to accelerate wound healing: trajectory and recent advancements

P Kolimi, S Narala, D Nyavanandi, AAA Youssef… - Cells, 2022 - mdpi.com
Wound healing is highly specialized dynamic multiple phase process for the repair of
damaged/injured tissues through an intricate mechanism. Any failure in the normal wound …

The role of autophagy in bone metabolism and clinical significance

J Wang, Y Zhang, J Cao, Y Wang, N Anwar, Z Zhang… - Autophagy, 2023 - Taylor & Francis
The skeletal system is the basis of the vertebral body composition, which affords stabilization
sites for muscle attachment, protects vital organs, stores mineral ions, supplies places to the …

Sustained oxygenation accelerates diabetic wound healing by promoting epithelialization and angiogenesis and decreasing inflammation

Y Guan, H Niu, Z Liu, Y Dang, J Shen, M Zayed… - Science …, 2021 - science.org
Nonhealing diabetic wounds are common complications for diabetic patients. Because
chronic hypoxia prominently delays wound healing, sustained oxygenation to alleviate …

Skin tissue engineering: wound healing based on stem-cell-based therapeutic strategies

A Nourian Dehkordi, F Mirahmadi Babaheydari… - Stem cell research & …, 2019 - Springer
Normal wound healing is a dynamic and complex multiple phase process involving
coordinated interactions between growth factors, cytokines, chemokines, and various cells …

Autophagy and skin wound healing

H Ren, F Zhao, Q Zhang, X Huang, Z Wang - Burns & trauma, 2022 - academic.oup.com
Autophagy is a lysosome-dependent, self-renewal mechanism that can degrade and recycle
cellular components in eukaryotic cells to maintain the stability of the intracellular …

Cationic, anionic and neutral polysaccharides for skin tissue engineering and wound healing applications

H Nosrati, M Khodaei, Z Alizadeh… - International journal of …, 2021 - Elsevier
Today, chronic wound care and management can be regarded as a clinically critical issue.
However, the limitations of current approaches for wound healing have encouraged …

Overexpression of VEGF in dermal fibroblast cells accelerates the angiogenesis and wound healing function: in vitro and in vivo studies

F Shams, H Moravvej, S Hosseinzadeh, E Mostafavi… - Scientific reports, 2022 - nature.com
Fibroblasts are the main cells of connective tissue and have pivotal roles in the proliferative
and maturation phases of wound healing. These cells can secrete various cytokines, growth …

Exosomes derived from mmu_circ_0000250-modified adipose-derived mesenchymal stem cells promote wound healing in diabetic mice by inducing miR-128-3p …

R Shi, Y **, W Hu, W Lian, C Cao… - … of Physiology-Cell …, 2020 - journals.physiology.org
More and more evidence advises that circular RNAs (circRNAs) function critically in
regulating different disease microenvironments. Our previous study found that …

Nanozyme-Integrated Thermoresponsive In Situ Forming Hydrogel Enhances Mesenchymal Stem Cell Viability and Paracrine Effect for Efficient Spinal Cord Repair

L Xu, J Mu, Z Ma, P Lin, F **a, X Hu, J Wu… - … Applied Materials & …, 2023 - ACS Publications
Mesenchymal stem cell (MSC)-based therapy has emerged as a promising strategy for the
treatment of spinal cord injury (SCI). However, the hostile microenvironment of SCI, which …

Fabrication of chitosan/PVP/dihydroquercetin nanocomposite film for in vitro and in vivo evaluation of wound healing

J Zhang, K Chen, C Ding, S Sun, Y Zheng… - International Journal of …, 2022 - Elsevier
The high cost of wound healing treatment, the slow recovery of wounds, and the uncertainty
of being affected by the body's physiological activities constitute a serious burden on public …