GNN Codon Adjacency Tunes Protein Translation

J Sun, P Hwang, ED Sakkas, Y Zhou, L Perez… - International Journal of …, 2024 - mdpi.com
The central dogma treats the ribosome as a molecular machine that reads one mRNA codon
at a time as it adds each amino acid to its growing peptide chain. However, this and previous …

[HTML][HTML] The CAR–mRNA Interaction Surface Is a Zipper Extension of the Ribosome A Site

C Dalgarno, K Scopino, M Raval… - International Journal of …, 2022 - mdpi.com
The ribosome CAR interaction surface behaves as an extension of the decoding center A
site and has H-bond interactions with the+ 1 codon, which is next in line to enter the A site …

CNNArginineMe: A CNN structure for training models for predicting arginine methylation sites based on the One-Hot encoding of peptide sequence

J Zhao, H Jiang, G Zou, Q Lin, Q Wang, J Liu… - Frontiers in …, 2022 - frontiersin.org
Protein arginine methylation (PRme), as one post-translational modification, plays a critical
role in numerous cellular processes and regulates critical cellular functions. Though several …

The Mechanism of Bimodal Effect of DL-Butyonine Sulfoximine on Constitutive Androstane and Pregnane X Receptors In Vitro

YV Abalenikhina, AV Shchulkin, AA Seidkulieva… - Molecular Biology, 2023 - Springer
The constitutive androstane receptor (CAR) and the pregnane X receptor (PXR) are nuclear
receptors that are involved in the regulation of gene transcription of enzymes that are …

Effect of the Nitric Oxide Donor S-Nitrosoglutathione on Expression of the Constitutive Androstane Receptor

YV Abalenikhina, EA Sudakova… - Journal of Evolutionary …, 2022 - Springer
The mechanisms of regulation of the constitutive androstane receptor (CAR) under the effect
of the nitric oxide (NO) donor S-nitrosoglutathione (GSNO), added to a nutrient medium at …

GNN codon adjacency regulates protein translation

J Sun, P Hwang, ED Sakkas, Y Zhou, L Perez, I Dave… - bioRxiv, 2024 - biorxiv.org
The central dogma treats the ribosome as a molecular machine that reads one mRNA codon
at a time as it adds each amino acid to its growing peptide chain. However, this and previous …

Влияние донора оксида азота S-нитрозоглутатиона на экспрессию конститутивного андростанового рецептора

ЮВ Абаленихина, ЕА Судакова… - Журнал …, 2022 - rusjphysiol.org
Аннотация Настоящая работа посвящена изучению механизмов регуляции
конститутивного андростанового рецептора (CAR) при воздействии донора оксида …

Deciphering context-dependent amber suppression efficiency in mammalian cells with an expanded genetic code

MD Bartoschek - 2021 - edoc.ub.uni-muenchen.de
The genetic code of organisms can be expanded by introducing orthogonal translation
systems (OTSs). One of the most commonly applied OTSs in mammalian cells is the …

[CITATION][C] Probing Putative MRNA/CAR Interactions Through Ribosome Profiling

HB Kwon - 2022 - Wesleyan University

[CITATION][C] Wobble Nucleotide of A-site tRNA Anticodon and Function of CAR Interaction Surface

Y Zhou - 2024 - Wesleyan University