The rapid emergence of antifungal-resistant human-pathogenic fungi

SR Lockhart, A Chowdhary, JAW Gold - Nature Reviews Microbiology, 2023 - nature.com
During recent decades, the emergence of pathogenic fungi has posed an increasing public
health threat, particularly given the limited number of antifungal drugs available to treat …

Candida auris: Epidemiology, biology, antifungal resistance, and virulence

H Du, J Bing, T Hu, CL Ennis, CJ Nobile… - PLoS …, 2020 - journals.plos.org
First described in 2009 in Japan, the emerging multidrug-resistant fungal pathogen Candida
auris is becoming a worldwide public health threat that has been attracting considerable …

Worsening Spread of Candida auris in the United States, 2019 to 2021

M Lyman, K Forsberg, DJ Sexton, NA Chow… - Annals of Internal …, 2023 - acpjournals.org
Background: Candida auris is an emerging fungal threat that has been spreading in the
United States since it was first reported in 2016. Objective: To describe recent changes in …

Global and multi-national prevalence of fungal diseases—estimate precision

F Bongomin, S Gago, RO Oladele, DW Denning - Journal of fungi, 2017 - mdpi.com
Fungal diseases kill more than 1.5 million and affect over a billion people. However, they are
still a neglected topic by public health authorities even though most deaths from fungal …

[HTML][HTML] Resistance of Candida to azoles and echinocandins worldwide

KE Pristov, MA Ghannoum - Clinical Microbiology and Infection, 2019 - Elsevier
Background Recently there has been an increase in Candida infections worldwide. A
handful of species in the genus Candida are opportunistic pathogens and have been known …

Detection and characterisation of a sixth Candida auris clade in Singapore: a genomic and phenotypic study

C Suphavilai, KKK Ko, KM Lim, MG Tan… - The Lancet …, 2024 - thelancet.com
Background The emerging fungal pathogen Candida auris poses a serious threat to global
public health due to its worldwide distribution, multidrug resistance, high transmissibility …

Candida auris: a review of the literature

A Jeffery-Smith, SK Taori, S Schelenz… - Clinical microbiology …, 2018 - Am Soc Microbiol
The emerging pathogen Candida auris has been associated with nosocomial outbreaks on
five continents. Genetic analysis indicates the simultaneous emergence of separate clades …

Multidrug-Resistant Candida: Epidemiology, Molecular Mechanisms, and Treatment

MC Arendrup, TF Patterson - The Journal of infectious diseases, 2017 - academic.oup.com
Invasive Candida infections remain an important cause of morbidity and mortality, especially
in hospitalized and immunocompromised or critically ill patients. A limited number of …

Tracing the evolutionary history and global expansion of Candida auris using population genomic analyses

NA Chow, JF Muñoz, L Gade, EL Berkow, X Li… - MBio, 2020 - Am Soc Microbiol
Candida auris has emerged globally as a multidrug-resistant yeast that can spread via
nosocomial transmission. An initial phylogenetic study of isolates from Japan, India …

Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally

A Chowdhary, C Sharma, JF Meis - PLOS pathogens, 2017 - journals.plos.org
Candidiasis, which includes both superficial infections and invasive disease, is the most
common cause of fungal infection worldwide. Candida bloodstream infections (BSI) cause …