Developments of Polysorbate (Tween) based microemulsions: Preclinical drug delivery, toxicity and antimicrobial applications
G Kaur, SK Mehta - International journal of pharmaceutics, 2017 - Elsevier
The present review deals with the progress of Polysorbates (Tween) based microemulsions
in drug delivery. PEGylated Sorbitan Fatty Acid Esters (Tweens/Polysorbates) are one of the …
in drug delivery. PEGylated Sorbitan Fatty Acid Esters (Tweens/Polysorbates) are one of the …
[HTML][HTML] The promising future of nano-antioxidant therapy against environmental pollutants induced-toxicities
Developmental toxicity caused by exposure to a mixture of environmental pollutants has
become a major health concern. Human-made chemicals, including xenoestrogens …
become a major health concern. Human-made chemicals, including xenoestrogens …
Free Radical-Scavenging, Anti-Inflammatory/Anti-Fibrotic and Hepatoprotective Actions of Taurine and Silymarin against CCl4 Induced Rat Liver Damage
AM Abdel-Moneim, MA Al-Kahtani, MA El-Kersh… - PloS one, 2015 - journals.plos.org
The present study aims to investigate the hepatoprotective effect of taurine (TAU) alone or in
combination with silymarin (SIL) on CCl4-induced liver damage. Twenty five male rats were …
combination with silymarin (SIL) on CCl4-induced liver damage. Twenty five male rats were …
Formulation of nanomicelles to improve the solubility and the oral absorption of silymarin
Two novel nanomicellar formulations were developed to improve the poor aqueous
solubility and the oral absorption of silymarin. Polymeric nanomicelles made of Soluplus and …
solubility and the oral absorption of silymarin. Polymeric nanomicelles made of Soluplus and …
Pharmacokinetic and pharmacodynamic features of nanoemulsion following oral, intravenous, topical and nasal route
Background: Most of the active pharmaceutical ingredients discovered recently in
pharmaceutical field exhibits poor aqueous solubility that pose major problem in their oral …
pharmaceutical field exhibits poor aqueous solubility that pose major problem in their oral …
Oral bioavailability enhancement and hepatoprotective effects of thymoquinone by self-nanoemulsifying drug delivery system
Thymoquinone (TQ) is a poorly water soluble bioactive compound which shows poor oral
bioavailability upon oral administration. Due to poor aqueous solubility and bioavailability of …
bioavailability upon oral administration. Due to poor aqueous solubility and bioavailability of …
Carbon tetrachloride-induced hepatotoxicity in rat is reversed by treatment with riboflavin
Liver is a vital organ for the detoxification of toxic substances present in the body and
hepatic injury is associated with excessive exposure to toxicants. The present study was …
hepatic injury is associated with excessive exposure to toxicants. The present study was …
Protective effect of polysaccharide from maca (Lepidium meyenii) on Hep-G2 cells and alcoholic liver oxidative injury in mice
L Zhang, Q Zhao, L Wang, M Zhao, B Zhao - International journal of …, 2017 - Elsevier
To study the characterization and hepatoprotective activity of polysaccharide from maca
(Lepidium meyenii), the main polysaccharide from maca (MP-1) was obtained by DEAE-52 …
(Lepidium meyenii), the main polysaccharide from maca (MP-1) was obtained by DEAE-52 …
Hepatoprotective Role of Ethanolic Extract of Vitex negundo in Thioacetamide‐Induced Liver Fibrosis in Male Rats
FA Kadir, NM Kassim, MA Abdulla… - Evidence‐Based …, 2013 - Wiley Online Library
The hepatoprotective activity of ethanolic extract from the leaves of Vitex negundo (VN) was
conducted against thioacetamide‐(TAA‐) induced hepatic injury in Sprague Dawley rats …
conducted against thioacetamide‐(TAA‐) induced hepatic injury in Sprague Dawley rats …
Lipid-based nanocarriers as an alternative for oral delivery of poorly water-soluble drugs: peroral and mucosal routes
AC Silva, D Santos, D Ferreira… - Current medicinal …, 2012 - ingentaconnect.com
The hydrophobic character of most drug molecules and their potential for degradation under
the hostile environment of the gastrointestinal tract (GIT) constitutes the main obstacle in the …
the hostile environment of the gastrointestinal tract (GIT) constitutes the main obstacle in the …