Nutrient-induced cellular mechanisms of gut hormone secretion
VB Lu, FM Gribble, F Reimann - Nutrients, 2021 - mdpi.com
The gastrointestinal tract can assess the nutrient composition of ingested food. The nutrient-
sensing mechanisms in specialised epithelial cells lining the gastrointestinal tract, the …
sensing mechanisms in specialised epithelial cells lining the gastrointestinal tract, the …
Molecular mechanisms underlying nutrient-stimulated incretin secretion
HE Parker, F Reimann, FM Gribble - Expert reviews in molecular …, 2010 - cambridge.org
The incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent
insulinotropic polypeptide (GIP) are released from enteroendocrine cells in the intestinal …
insulinotropic polypeptide (GIP) are released from enteroendocrine cells in the intestinal …
Intestinal sensing of nutrients
G Tolhurst, F Reimann, FM Gribble - Appetite Control, 2012 - Springer
Ingestion of a meal triggers a range of physiological responses both within and outside the
gut, and results in the remote modulation of appetite and glucose homeostasis. Luminal …
gut, and results in the remote modulation of appetite and glucose homeostasis. Luminal …
The gut endocrine system as a coordinator of postprandial nutrient homoeostasis
FM Gribble - Proceedings of the Nutrition Society, 2012 - cambridge.org
Hormones from the gastrointestinal (GI) tract are released following food ingestion and
trigger a range of physiological responses including the coordination of appetite and …
trigger a range of physiological responses including the coordination of appetite and …
[HTML][HTML] Diet: friend or foe of enteroendocrine cells: how it interacts with enteroendocrine cells
Gut hormones play a key role in the regulation of food intake, energy expenditure, glucose
homeostasis, lipid metabolism, and a wide range of metabolic functions in response to food …
homeostasis, lipid metabolism, and a wide range of metabolic functions in response to food …
Enteroendocrine hormone secretion and metabolic control: importance of the region of the gut stimulation
It is now widely appreciated that gastrointestinal function is central to the regulation of
metabolic homeostasis. Following meal ingestion, the delivery of nutrients from the stomach …
metabolic homeostasis. Following meal ingestion, the delivery of nutrients from the stomach …
Effects of a novel combination of orlistat and acarbose on tolerability, appetite, and glucose metabolism in persons with obesity
U Holmbäck, A Forslund, S Grudén… - Obesity science & …, 2020 - Wiley Online Library
Objective There is an unmet medical need for a safe and effective weight loss product with
minimal systemic side‐effects. In this study, the effect of a novel modified‐release fixed‐dose …
minimal systemic side‐effects. In this study, the effect of a novel modified‐release fixed‐dose …
[HTML][HTML] Molecular mechanisms underlying nutrient detection by incretin-secreting cells
F Reimann - International dairy journal, 2010 - Elsevier
The hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like
peptide-1 (GLP-1) are secreted postprandially from intestinal K-and L-cells, respectively. As …
peptide-1 (GLP-1) are secreted postprandially from intestinal K-and L-cells, respectively. As …
Pros and cons of fatty acids in bone biology
F Wauquier, L Leotoing, C Philippe, M Spilmont… - Progress in lipid …, 2015 - Elsevier
Despite the growing interest in deciphering the causes and consequences of obesity-related
disorders, the mechanisms linking fat intake to bone behaviour remain unclear. Since bone …
disorders, the mechanisms linking fat intake to bone behaviour remain unclear. Since bone …
Revisiting the concept of incretin and enteroendocrine L-cells as type 2 diabetes mellitus treatment
The significant growth in type 2 diabetes mellitus (T2DM) prevalence strikes a common
threat to the healthcare and economic systems globally. Despite the availability of several …
threat to the healthcare and economic systems globally. Despite the availability of several …