Ion channels are membrane proteins expressed in almost all living cells. The sequencing of
the human genome has identified more than 400 putative ion channels, but only a fraction of …

About 10 distinct potassium channels in the heart are involved in sha** the action
potential. Some of the K+ channels are primarily responsible for early repolarization …

Background—Recent evidence points to functional Ca2+-dependent K+ (SK) channels in
the heart that may govern atrial fibrillation (AF) risk, but the underlying mechanisms are …

An efficient and versatile iron phthalocyanine catalyzed method has been developed for N-
alkylation of various amines with alcohols. Readily available alcohols were used as …

The application of nontoxic, earth-abundant transition metals in place of costly noble metals
is a paramount goal in catalysis and is especially interesting if the air-and moisture-stable …

The three small-conductance calcium-activated potassium (KCa2) channels and the related
intermediate-conductance KCa3. 1 channel are voltage-independent K+ channels that …

Background—Recently, evidence has emerged that small-conductance Ca2+-activated K+
(SK) channels are predominantly expressed in the atria in a number of species including …

Chiral trans-cyclohexanediamine-benzimidazole organocatalysts promote the conjugate
addition of a wide variety of 1, 3-dicarbonyl compounds such as malonates, ketoesters, and …

BACKGROUND AND PURPOSE Transient receptor potential cation channel subfamily M
member 7 (TRPM7) is a bifunctional protein comprising a TRP ion channel segment linked …

Brief periods of ischemia are known to confer to the myocardium an increased resistance to
the injury due to a later and more prolonged ischemic episode. This phenomenon, known as …