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The life and times of a tRNA
The study of eukaryotic tRNA processing has given rise to an explosion of new information
and insights in the last several years. We now have unprecedented knowledge of each step …
and insights in the last several years. We now have unprecedented knowledge of each step …
Recognition of the tRNA structure: Everything everywhere but not all at once
J Zhang - Cell chemical biology, 2024 - cell.com
Summary tRNAs are among the most abundant and essential biomolecules in cells. These
spontaneously folding, extensively structured yet conformationally flexible anionic polymers …
spontaneously folding, extensively structured yet conformationally flexible anionic polymers …
A tRNA-specific function for tRNA methyltransferase Trm10 is associated with a new tRNA quality control mechanism in Saccharomyces cerevisiae
IE Bowles, JE Jackman - Rna, 2024 - rnajournal.cshlp.org
In Saccharomyces cerevisiae, a single homolog of the tRNA methyltransferase Trm10
performs m1G9 modification on 13 different tRNAs. Here we provide evidence that the m1G9 …
performs m1G9 modification on 13 different tRNAs. Here we provide evidence that the m1G9 …
Free introns of tRNAs as complementarity-dependent regulators of gene expression
From archaea to humans, a subset of transfer RNA (tRNA) genes possesses an intron that
must be removed from transcribed pre-tRNAs to generate mature, functional tRNAs …
must be removed from transcribed pre-tRNAs to generate mature, functional tRNAs …
Phosphate-dependent nuclear export via a novel NES class recognized by exportin Msn5
Gene expression in response to environmental stimuli is dependent on nuclear localization
of key signaling components, which can be tightly regulated by phosphorylation. This is …
of key signaling components, which can be tightly regulated by phosphorylation. This is …
In vivo cross-linking and co-immunoprecipitation procedure to analyze nuclear tRNA export complexes in yeast cells
Abstract tRNAs are small noncoding RNAs that are predominantly known for their roles in
protein synthesis and also participate in numerous other functions ranging from retroviral …
protein synthesis and also participate in numerous other functions ranging from retroviral …
Gle1 is required for tRNA to stimulate Dbp5 ATPase activity in vitro and to promote Dbp5 mediated tRNA export in vivo
AAN Rajan, R Asada, B Montpetit - bioRxiv, 2023 - pmc.ncbi.nlm.nih.gov
Cells must maintain a pool of processed and charged transfer RNAs (tRNA) to sustain
translation capacity and efficiency. Numerous parallel pathways support the processing and …
translation capacity and efficiency. Numerous parallel pathways support the processing and …
Investigating a Role for the DEAD-box Protein 5 (Dbp5) in tRNA Regulation
A Arul Nambi Rajan - 2023 - escholarship.org
Eukaryotic gene expression is compartmentalized with transcription of genetic information
from DNA into messenger RNA (mRNA) occurring in the nucleus and translation of these …
from DNA into messenger RNA (mRNA) occurring in the nucleus and translation of these …
[KNIHA][B] Investigating a Role for the Dead-Box Protein 5 (Dbp5) in tRNA Regulation
AAN Rajan - 2023 - search.proquest.com
Eukaryotic gene expression is compartmentalized with transcription of genetic information
from DNA into messenger RNA (mRNA) occurring in the nucleus and translation of these …
from DNA into messenger RNA (mRNA) occurring in the nucleus and translation of these …
Gle1 is required for tRNA to stimulate Dbp5 ATPase activity in vitro and promote Dbp5-mediated tRNA export in vivo in Saccharomyces cerevisiae
AAN Rajan, R Asada, B Montpetit - Elife, 2024 - elifesciences.org
Cells must maintain a pool of processed and charged transfer RNAs (tRNA) to sustain
translation capacity and efficiency. Numerous parallel pathways support the processing and …
translation capacity and efficiency. Numerous parallel pathways support the processing and …