Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities
C Vilchèze, WR Jacobs Jr - Molecular genetics of Mycobacteria, 2014 - Wiley Online Library
Tuberculosis (TB) chemotherapy started in the 1930s with the discovery by Domagk and
colleagues of the anti‐TB activity of sulfonamides. Since these compounds were very toxic …
colleagues of the anti‐TB activity of sulfonamides. Since these compounds were very toxic …
Evaluation of Genetic Mutations Associated with Mycobacterium tuberculosis Resistance to Amikacin, Kanamycin and Capreomycin: A Systematic Review
Background Rapid molecular diagnostics for detecting multidrug-resistant and extensively
drug-resistant tuberculosis (M/XDR-TB) primarily identify mutations in Mycobacterium …
drug-resistant tuberculosis (M/XDR-TB) primarily identify mutations in Mycobacterium …
Application of Mycobacterium smegmatis as a surrogate to evaluate drug leads against Mycobacterium tuberculosis
Discovery of new anti-tuberculosis (TB) drugs is a time-consuming process due to the slow-
growing nature of Mycobacterium tuberculosis (Mtb). A requirement of biosafety level 3 (BSL …
growing nature of Mycobacterium tuberculosis (Mtb). A requirement of biosafety level 3 (BSL …
Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis: a new strategy to revisit mycobacterial targets and repurpose old drugs
L Rodrigues, P Cravo, M Viveiros - Expert review of anti-infective …, 2020 - Taylor & Francis
ABSTRACT Introduction: In 2018, an estimated 377,000 people developed multidrug-
resistant tuberculosis (MDR-TB), urging for new effective treatments. In the last years, it has …
resistant tuberculosis (MDR-TB), urging for new effective treatments. In the last years, it has …
Prevalence of drug-resistant pulmonary tuberculosis in India: systematic review and meta-analysis
V Goyal, V Kadam, P Narang, V Singh - BMC Public Health, 2017 - Springer
Background Drug-resistant pulmonary tuberculosis (DR-TB) is a significant public health
issue that considerably deters the ongoing TB control efforts in India. The purpose of this …
issue that considerably deters the ongoing TB control efforts in India. The purpose of this …
Extensively drug-resistant tuberculosis in India: Current evidence on diagnosis & management
R Prasad, A Singh, V Balasubramanian… - Indian Journal of …, 2017 - journals.lww.com
Emergence of extensively drug-resistant tuberculosis (XDR-TB) has significantly threatened
to jeopardize global efforts to control TB, especially in HIV endemic regions. XDR-TB is …
to jeopardize global efforts to control TB, especially in HIV endemic regions. XDR-TB is …
Characterization of mutations conferring extensive drug resistance to Mycobacterium tuberculosis isolates in Pakistan
The increasing incidence of extensively drug-resistant (XDR) Mycobacterium tuberculosis in
high-tuberculosis-burden countries further highlights the need for improved rapid diagnostic …
high-tuberculosis-burden countries further highlights the need for improved rapid diagnostic …
Incidence and risk factors for extensively drug-resistant tuberculosis in Delhi region
Background India with a major burden of multidrug-resistant tuberculosis (MDR-TB) does
not have national level data on this hazardous disease. Since 2006, emergence of …
not have national level data on this hazardous disease. Since 2006, emergence of …
Dual antituberculosis drugs-loaded gelatin hydrogel bioimplant for treating spinal tuberculosis
Spinal tuberculosis (TB) represents around 1% of the recorded TB with a high mortality rate
due to neurological complications and kyphosis. The current work aimed to develop a …
due to neurological complications and kyphosis. The current work aimed to develop a …
[HTML][HTML] Analysis of drug resistance mutations in pulmonary Mycobacterium tuberculosis isolates in the Southern coastal region of Andhra Pradesh, India
PG Prasad, MS Jasmine, K Deepthi… - Brazilian Journal of …, 2019 - SciELO Brasil
Purpose and objectives Detection of drug resistance plays a crucial role in tuberculosis (TB)
treatment and prevention of Mycobacterium tuberculosis (MTB) transmission. The aim of this …
treatment and prevention of Mycobacterium tuberculosis (MTB) transmission. The aim of this …