Although the coordination chemistry of N-heterocyclic carbenes (NHCs) with transition
metals has been explored for half a century, only in the past ten years has the chemistry of …

The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

Silver has been used for numerous medical conditions for centuries, however, most of the
current clinical silver agents all have their own disadvantages limiting the clinical …

Because of their great structural diversity and multitude of chemical properties, N-
heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently …

N-heterocyclic carbenes (NHCs) are organic compounds that typically mimic the chemical
properties of phosphines. NHCs have made a significant impact on the field of coordination …

The ligand quantity, ligand type, and coordination geometry have important influences on
the anticancer activity of metal-based complexes. On the basis of the structures of previously …

New weapons are constantly needed in the fight against cancer. The discovery of cisplatin
as an anticancer drug prompted the search for new metal complexes. The successful history …

Synthesis and anticancer studies of three symmetrically and non-symmetrically substituted
silver (I)-N-Heterocyclic carbene complexes of type [(NHC) 2-Ag] PF 6 (7–9) and their …

A new series of N-Heterocyclic carbene based ligands and their silver (I) complexes was
obtained and tested in vitro on three bacterial strains (Bacillus subtillis, Bacillus cereus and …

In this study, we synthesized four novel unsymmetrically substituted NHC ligands (1a-d) and
their Ag (I) complexes (2a-d). All new compounds were characterized using elemental …