Performance monitoring is an important executive function that allows us to gain insight into
our own behaviour. This remarkable ability relies on the frontal cortex, and its impairment is …

Movement disorders such as Parkinson's disease (PD) impact oculomotor function–the
ability to move the eyes accurately and purposefully to serve a multitude of sensory …

Recurrently connected networks of spiking neurons underlie the astounding information
processing capabilities of the brain. Yet in spite of extensive research, how they can learn …

Controlling behavior to flexibly achieve desired goals depends on the ability to monitor one's
own performance. It is unknown how performance monitoring can be both flexible, to support …

Different regions of the striatum regulate different types of behavior. However, how
dopamine signals differ across striatal regions and how dopamine regulates different …

Highlights•Humans and animals seek information about uncertain future
rewards.•Information is valued for resolving uncertainty and signaling desirable …

Humans and other primates have a remarkable ability to perform a wide range of tasks and
behaviors, even novel ones, in order to achieve their goals. Further, they are able to shift …

The medial frontal cortex (MFC) enables executive control by monitoring relevant
information and using it to adapt behavior. In macaques performing a saccade …

Brains learn tasks via experience-driven differential adjustment of their myriad individual
synaptic connections, but the mechanisms that target appropriate adjustment to particular …

The marriage of cognitive neurophysiology and mathematical psychology to understand
decision-making has been exceptionally productive. This interdisciplinary area is based on …