Thyroid hormones, oxidative stress, and inflammation

A Mancini, C Di Segni, S Raimondo… - Mediators of …, 2016 - Wiley Online Library
Inflammation and oxidative stress (OS) are closely related processes, as well exemplified in
obesity and cardiovascular diseases. OS is also related to hormonal derangement in a …

Insulin resistance associated to obesity: the link TNF-alpha

I Nieto-Vazquez, S Fernández-Veledo… - … of physiology and …, 2008 - Taylor & Francis
Adipose tissue secretes proteins which may influence insulin sensitivity. Among them,
tumour necrosis factor (TNF)-alpha has been proposed as a link between obesity and …

Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice

J Ye, Z Gao, J Yin, Q He - American Journal of Physiology …, 2007 - journals.physiology.org
Chronic inflammation and reduced adiponectin are widely observed in the white adipose
tissue in obesity. However, the cause of the changes remains to be identified. In this study …

The telomerase activator TA‐65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence

BB de Jesus, K Schneeberger, E Vera, A Tejera… - Aging cell, 2011 - Wiley Online Library
Here, we show that a small‐molecule activator of telomerase (TA‐65) purified from the root
of Astragalus membranaceus is capable of increasing average telomere length and …

Effects of food-derived bioactive peptides on cognitive deficits and memory decline in neurodegenerative diseases: A review

S Wang, D Sun-Waterhouse, GIN Waterhouse… - Trends in Food Science …, 2021 - Elsevier
Background Memory and cognitive impairments/disorders are the main clinical symptoms of
neurodegenerative diseases. The prevalence of such chronic conditions has increased over …

Characterization and Exploration of Potential Neuroprotective Peptides in Walnut (Juglans regia) Protein Hydrolysate against Cholinergic System Damage and …

S Wang, G Su, X Zhang, G Song, L Zhang… - Journal of agricultural …, 2021 - ACS Publications
The purpose of this study was to determine the neuroprotective effect and mechanism of
walnut protein hydrolysates (WPH) against memory deficits induced by scopolamine in mice …

Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity

W Bakker, EC Eringa, P Sipkema… - Cell and tissue …, 2009 - Springer
Endothelial dysfunction comprises a number of functional alterations in the vascular
endothelium that are associated with diabetes and cardiovascular disease, including …

TNF-α in the cardiovascular system: from physiology to therapy

K Urschel, I Cicha - … Journal of Interferon, Cytokine and Mediator …, 2015 - Taylor & Francis
Signaling pathways induced by the proinflammatory cytokine tumor necrosis factor alpha
(TNF-α) play a key role in the cellular responses to inflammation and injury. In the …

Inhibitory Effects of Walnut (Juglans regia) Peptides on Neuroinflammation and Oxidative Stress in Lipopolysaccharide-Induced Cognitive Impairment Mice

S Wang, L Zheng, T Zhao, Q Zhang, Y Liu… - Journal of agricultural …, 2020 - ACS Publications
Increasing level of inflammation and oxidative stress could lead to memory impairment. The
purpose of this study was to determine the neuroprotective effects of walnut peptides against …

Interaction of IL-6 and TNF-α contributes to endothelial dysfunction in type 2 diabetic mouse hearts

J Lee, S Lee, H Zhang, MA Hill, C Zhang, Y Park - PloS one, 2017 - journals.plos.org
Objectives Inflammatory cytokines, such as tumor necrosis factor-α (TNF-α) and interleukin-6
(IL-6), are individually considered as important contributors to endothelial dysfunction in …