Bifunctional gallium-68 chelators: Past, present, and future
P Spang, C Herrmann, F Roesch - Seminars in nuclear medicine, 2016 - Elsevier
This article reviews the development of bifunctional chelates for synthesising 68 Ga
radiopharmaceuticals. It structures the chelates into groups of macrocycles …
radiopharmaceuticals. It structures the chelates into groups of macrocycles …
The chemistry and biology of organic guanidine derivatives
RGS Berlinck, AE Trindade-Silva… - Natural Product …, 2012 - pubs.rsc.org
Covering: 2010 and 2011. Previous review: Nat. Prod. Rep., 2010, 27, 1871 The chemistry
and biology of organic natural guanidines are reviewed, including the isolation, structure …
and biology of organic natural guanidines are reviewed, including the isolation, structure …
New tris (hydroxypyridinone) bifunctional chelators containing isothiocyanate groups provide a versatile platform for rapid one-step labeling and PET imaging with …
Two new bifunctional tris (hydroxypyridinone)(THP) chelators designed specifically for rapid
labeling with 68Ga have been synthesized, each with pendant isothiocyanate groups and …
labeling with 68Ga have been synthesized, each with pendant isothiocyanate groups and …
Gallium (III) complexes of NOTA‐bis (phosphonate) conjugates as PET radiotracers for bone imaging
J Holub, M Meckel, V Kubíček, F Rösch… - Contrast Media & …, 2015 - Wiley Online Library
Ligands with geminal bis (phosphonic acid) appended to 1, 4, 7‐triazacyclonone‐1, 4‐
diacetic acid fragment through acetamide (NOTAMBP) or methylenephosphinate …
diacetic acid fragment through acetamide (NOTAMBP) or methylenephosphinate …
H2hox: Dual-Channel Oxine-Derived Acyclic Chelating Ligand for 68Ga Radiopharmaceuticals
An acyclic hexadentate oxine-derived chelating ligand, H2hox, was investigated as an
alternative to current chelators for 68Ga. The straightforward preparation of H2hox, involving …
alternative to current chelators for 68Ga. The straightforward preparation of H2hox, involving …
Peptide synthesis, characterization and 68Ga-radiolabeling of NOTA-conjugated ubiquicidin fragments for prospective infection imaging with PET/CT
Introduction Human antimicrobial peptides are of interest for the development of positron
emission tomography (PET) tracers as they exhibit desirable characteristics that make them …
emission tomography (PET) tracers as they exhibit desirable characteristics that make them …
Rapid kit-based 68Ga-labelling and PET imaging with THP-Tyr3-octreotate: a preliminary comparison with DOTA-Tyr3-octreotate
Abstract Background Ge/68 Ga generators provide an inexpensive source of a PET isotope
to hospitals without cyclotron facilities. The development of new 68 Ga-based molecular …
to hospitals without cyclotron facilities. The development of new 68 Ga-based molecular …
Gallium-68 complex of a macrobicyclic cage amine chelator tethered to two integrin-targeting peptides for diagnostic tumor imaging
Tumor-targeting peptides radiolabeled with positron-emitting 68Ga are promising
candidates as new noninvasive diagnostic agents for positron emission tomography (PET) …
candidates as new noninvasive diagnostic agents for positron emission tomography (PET) …
H2CHXhox: Rigid Cyclohexane-Reinforced Nonmacrocyclic Chelating Ligand for [nat/67/68Ga]Ga3+
A rigid chiral acyclic chelator H2 CHX hox was synthesized and evaluated for Ga3+-based
radiopharmaceutical applications; it was compared to the previously reported hexadentate …
radiopharmaceutical applications; it was compared to the previously reported hexadentate …
Gallium (III) chelates of mixed phosphonate-carboxylate triazamacrocyclic ligands relevant to nuclear medicine: Structural, stability and in vivo studies
Three triaza macrocyclic ligands, H 6 NOTP (1, 4, 7-triazacyclononane-N, N′, N ″-
trimethylene phosphonic acid), H 4 NO2AP (1, 4, 7-triazacyclononane-N …
trimethylene phosphonic acid), H 4 NO2AP (1, 4, 7-triazacyclononane-N …