Vaccines can be highly effective tools in combating antimicrobial resistance as they reduce
infections caused by antibiotic-resistant bacteria and antibiotic consumption associated with …

Historically, epidemiological investigation and surveillance for bacterial antimicrobial
resistance (AMR) has relied on low-resolution isolate-based phenotypic analyses …

We investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–specific
antibodies and T-cell responses against SARS-CoV-2 and human coronavirus (HCoV) 229E …

Background Pneumococcal conjugate vaccines have reduced the incidence of invasive
pneumococcal disease, caused by vaccine serotypes, but non-vaccine-serotypes remain a …

Progress has been made in the prevention and treatment of community-acquired bacterial
meningitis during the past three decades but the burden of the disease remains high …

Characterizing the genetic diversity of pathogens within the host promises to greatly improve
surveillance and reconstruction of transmission chains. For bacteria, it also informs our …

Background Epidemiological studies are necessary to explore the effect of current
pneumococcal conjugate vaccines (PCVs) against antibiotic resistance, including the rise of …

Background Serotype 24F is one of the emerging pneumococcal serotypes after the
introduction of pneumococcal conjugate vaccine (PCV). We aimed to identify lineages …

Capsular polysaccharide (CPS), which surrounds the bacteria, is one of the most significant
and multifaceted contributors to Streptococcus pneumoniae virulence. Capsule prevents …

As whole-genome sequencing capacity becomes increasingly decentralized, there is a
growing opportunity for collaboration and the sharing of surveillance data within and …