A prominent health issue nowadays is the COVID-19 pandemic, which poses acute risks to
human health. However, the long-term health consequences are largely unknown and …

High mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that is present in almost
all cells and regulates the activity of innate immune responses in both intracellular and …

Introduction Global warming augments the risk of adverse pregnancy outcomes in
vulnerable expectant mothers. Pioneering investigations into heat stress (HS) have …

Objective: The prevalence of sleep disorders during the perinatal period is high and large
health administrative database surveys have shown that the use of exogenous melatonin in …

Human pregnancy is a sequence of events finely tuned by several molecular interactions
that come with a new birth. The precise interlocking of these events affecting the …

Sleep disturbances are common in pregnancy, and sleep disorders may worsen or present
de novo in the course of gestation. Managing a pregnant patient is complicated by the risk of …

Melatonin is an endogenous pleiotropic molecule which orchestrates regulatory functions
and protective capacity against age‐related ailments. The increase in circulating levels of …

The term 'perinatal environment'refers to the period surrounding birth, which plays a crucial
role in brain development. It has been suggested that dynamic communication between the …

Problem Maternal inflammation leads to preterm birth and perinatal brain injury. Melatonin,
through its anti‐inflammatory effects, has been shown to be protective against inflammation …

Despite significant improvements in survival following preterm birth in recent years, the
neurodevelopmental burden of prematurity, with its long-term cognitive and behavioral …