Intracellular microbial rhodopsin-based optogenetics to control metabolism and cell signaling

AD Vlasova, SM Bukhalovich, DF Bagaeva… - Chemical Society …, 2024 - pubs.rsc.org
Microbial rhodopsin (MRs) ion channels and pumps have become invaluable optogenetic
tools for neuroscience as well as biomedical applications. Recently, MR-optogenetics …

Optogenetic engineering for ion channel modulation

T Wang, T Nonomura, TH Lan, Y Zhou - Current Opinion in Chemical …, 2025 - Elsevier
Optogenetics, which integrates photonics and genetic engineering to control protein activity
and cellular processes, has transformed biomedical research. Its precise spatiotemporal …

Guard cells count the number of unitary cytosolic Ca2+ signals to regulate stomatal dynamics

S Huang, MRG Roelfsema, M Gilliham… - Current Biology, 2024 - cell.com
Transient stimulus-specific increases in the cytosolic Ca 2+ concentration (" calcium
signatures") of guard cells have been proposed to regulate the opening and closure of …

Spatiotemporal dynamics of giant viruses within a deep freshwater lake reveal a distinct dark-water community

L Zhang, L Meng, Y Fang, H Ogata… - The ISME …, 2024 - academic.oup.com
Giant viruses (GVs) significantly regulate the ecological dynamics of diverse ecosystems.
Although metagenomics has expanded our understanding of their diversity and ecological …

Spatiotemporal dynamics revealed the dark water community of giant virus from a deep freshwater lake

L Zhang, L Meng, Y Fang, H Ogata, Y Okazaki - bioRxiv, 2024 - biorxiv.org
Giant viruses significantly regulate the ecological dynamics of diverse ecosystems. Although
metagenomics has expanded our understanding of their diversity and ecological roles …

Calcium-Sensitive Microbial Rhodopsin VirChR1: A Femtosecond to Second Photocycle Study

GHU Lamm, D Zabelskii, T Balandin… - The journal of …, 2024 - ACS Publications
Viral rhodopsins are light-gated cation channels representing a novel class of microbial
rhodopsins. For viral rhodopsin 1 subfamily members VirChR1 and OLPVR1, channel …

Unique hydrogen-bonding network in a viral channelrhodopsin

M Aoyama, K Katayama, H Kandori - Biochimica et Biophysica Acta (BBA) …, 2024 - Elsevier
Channelrhodopsins (CRs) are used as key tools in optogenetics, and novel CRs, either
found from nature or engineered by mutation, have greatly contributed to the development of …

[HTML][HTML] Photocontrôle de la concentration intracellulaire du calcium grâce à une rhodopsine d'origine virale-Application à la restauration du mouvement par la …

ÀS Eria-Oliveira, M Vivaudou - médecine/sciences, 2025 - medecinesciences.org
Identifiées dans le génome de virus géants, des protéines photoactivables de la famille des
rhodopsines se démarquent par leur comportement unique: elles résident dans les …