Mechanical state transitions in the regulation of tissue form and function
From embryonic development, postnatal growth and adult homeostasis to reparative and
disease states, cells and tissues undergo constant changes in genome activity, cell fate …
disease states, cells and tissues undergo constant changes in genome activity, cell fate …
Parsing patterns: Emerging roles of tissue self-organization in health and disease
Patterned morphologies, such as segments, spirals, stripes, and spots, frequently emerge
during embryogenesis through self-organized coordination between cells. Yet, complex …
during embryogenesis through self-organized coordination between cells. Yet, complex …
Inference and analysis of cell-cell communication using CellChat
Understanding global communications among cells requires accurate representation of cell-
cell signaling links and effective systems-level analyses of those links. We construct a …
cell signaling links and effective systems-level analyses of those links. We construct a …
[HTML][HTML] The developmental basis of fingerprint pattern formation and variation
Fingerprints are complex and individually unique patterns in the skin. Established prenatally,
the molecular and cellular mechanisms that guide fingerprint ridge formation and their …
the molecular and cellular mechanisms that guide fingerprint ridge formation and their …
Tracing the origin of hair follicle stem cells
R Morita, N Sanzen, H Sasaki, T Hayashi, M Umeda… - Nature, 2021 - nature.com
Tissue stem cells are generated from a population of embryonic progenitors through organ-
specific morphogenetic events,. Although tissue stem cells are central to organ homeostasis …
specific morphogenetic events,. Although tissue stem cells are central to organ homeostasis …
An updated classification of hair follicle morphogenesis
Hair follicle (HF) formation in develo** embryonic skin requires stepwise signalling
between the epithelial epidermis and mesenchymal dermis, and their specialized …
between the epithelial epidermis and mesenchymal dermis, and their specialized …
New developments in the biology of fibroblast growth factors
DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
Self-organization in pattern formation
F Schweisguth, F Corson - Developmental cell, 2019 - cell.com
Self-organization is pervasive in development, from symmetry breaking in the early embryo
to tissue patterning and morphogenesis. For a few model systems, the underlying molecular …
to tissue patterning and morphogenesis. For a few model systems, the underlying molecular …
Mathematical models for chemotaxis and their applications in self-organisation phenomena
KJ Painter - Journal of theoretical biology, 2019 - Elsevier
Chemotaxis is a fundamental guidance mechanism of cells and organisms, responsible for
attracting microbes to food, embryonic cells into develo** tissues, immune cells to …
attracting microbes to food, embryonic cells into develo** tissues, immune cells to …
Modern perspectives on near-equilibrium analysis of Turing systems
In the nearly seven decades since the publication of Alan Turing's work on morphogenesis,
enormous progress has been made in understanding both the mathematical and biological …
enormous progress has been made in understanding both the mathematical and biological …