EZH2 inhibition sensitizes MYC-high medulloblastoma cancers to PARP inhibition by regulating NUPR1-mediated DNA repair

J Yu, J Han, M Yu, H Rui, A Sun, H Li - Oncogene, 2024 - nature.com
MYC-driven medulloblastomas (MB) are highly aggressive pediatric brain tumors with poor
outcomes, and effective therapies remain limited despite intensive multimodal treatments …

Pentagalloyl glucose: a review of anticancer properties, molecular targets, mechanisms of action, pharmacokinetics, and safety profile

C Wen, N Dechsupa, Z Yu, X Zhang, S Liang, X Lei… - Molecules, 2023 - mdpi.com
Pentagalloyl glucose (PGG) is a natural hydrolyzable gallotannin abundant in various plants
and herbs. It has a broad range of biological activities, specifically anticancer activities, and …

Nanointerface engineering of MXene based Fe doped Bi2O3 nano heterostructures for efficient energy storage and environmental remediation

VA Mane, DV Dake, ND Raskar, RB Sonpir… - Journal of Energy …, 2025 - Elsevier
This study presents the synthesis of pure Bi 2 O 3 (PBO), Bi 2 O 3/MXene composite
(PBOM), and 5% Fe-doped Bi 2 O 3/MXene (FBOM5) via the hydrothermal method and …

Targeting UBE2T suppresses breast cancer stemness through CBX6-mediated transcriptional repression of SOX2 and NANOG

K Wang, Q He, X Jiang, T Wang, Z Li, H Qing, Y Dong… - Cancer Letters, 2025 - Elsevier
Breast cancer stem cells (BCSCs) are the main cause of breast cancer recurrence and
metastasis. While the ubiquitin-proteasome system contributes to the regulation of BCSC …

[HTML][HTML] Guar Gum-Modified Magnetic Palladium Nanocatalyst: CN Coupling Reaction and STAT3-Mediated Breast Cancer Therapy

J Luan, X Dong, S Zhou - Journal of Science: Advanced Materials and …, 2025 - Elsevier
The present study explains the unmoved synthesis of Pd nanoparticle-decorated guar gum
utilized as Fe 3 O 4 NPs (Fe 3 O 4@ guar gum/Pd NPs), the resultant catalytic and biological …

Multifunctional Fe-Doped Bi2O3/TiO2 Heterojunctions for Environmental Remediation and Gas Sensing

VA Mane, DV Dake, ND Raskar, RB Sonpir… - Surfaces and …, 2025 - Elsevier
In this study, we report the synthesis of Bi 2 O 3/TiO 2 (BTO) and 5% Fe-doped Bi 2 O 3/TiO 2
(FBTO5) pn type heterojunction nanocomposite using the hydrothermal method for …

Identification and evaluation of a novel parp1 inhibitor for the treatment of triple-negative breast cancer

R Gong, ZY Ma, LH He, SL Jiang, DS Cao… - Chemico-Biological …, 2023 - Elsevier
Triple-negative breast cancer (TNBC) is a particularly invasive subtype of breast cancer and
usually has a poor prognosis due to the lack of effective therapeutic targets. Approximately …

[HTML][HTML] A novel nanocarrier based on natural polyphenols enhancing gemcitabine sensitization ability for improved pancreatic cancer therapy efficiency

Y Dong, J Li, Y Dai, X Zhang, X Jiang, T Wang… - Materials Today Bio, 2025 - Elsevier
Pancreatic cancer (PC) is a highly lethal malignancy with rapid progression and poor
prognosis. Despite the widespread use of gemcitabine (Gem)-based chemotherapy as the …

Application of supported palladium nanoparticles over chitosan-agarose encapsulated Fe3O4 microspheres as efficient catalyst in the Sonogashira cross-coupling …

A Kakanejadifard, P Safarimehr, B Karmakar… - Journal of …, 2025 - Elsevier
In this work, a simple and modified method for immobilizing Pd (0) NPs on the surface of
dual functionalized magnetic Fe 3 O 4 microspheres with chitosan-agarose (CS-Agar) has …

Supported silver nanoparticles over starch-modified magnetic nanoparticles: Characterization, Its application for A3 coupling reactions, analgesic and anesthetic …

J Lu, M Zhang, AF El-kott, MA AlShehri, S Negm… - Journal of …, 2025 - Elsevier
This study focuses on the synthesis and characterization of silver nanoparticles (Ag NPs)
supported on starch-coated magnetic Fe 3 O 4 nanoparticles (Fe 3 O 4-starch/Ag NPs) using …