Profiling genome-wide DNA methylation

WS Yong, FM Hsu, PY Chen - Epigenetics & chromatin, 2016 - Springer
DNA methylation is an epigenetic modification that plays an important role in regulating
gene expression and therefore a broad range of biological processes and diseases. DNA …

Recent progress, methods and perspectives in forensic epigenetics

A Vidaki, M Kayser - Forensic Science International: Genetics, 2018 - Elsevier
Forensic epigenetics, ie, investigating epigenetics variation to resolve forensically relevant
questions unanswerable with standard forensic DNA profiling has been gaining substantial …

Systematic benchmarking of tools for CpG methylation detection from nanopore sequencing

ZWS Yuen, A Srivastava, R Daniel, D McNevin… - Nature …, 2021 - nature.com
DNA methylation plays a fundamental role in the control of gene expression and genome
integrity. Although there are multiple tools that enable its detection from Nanopore …

Portable nanopore-sequencing technology: Trends in development and applications

P Chen, Z Sun, J Wang, X Liu, Y Bai, J Chen… - Frontiers in …, 2023 - frontiersin.org
Sequencing technology is the most commonly used technology in molecular biology
research and an essential pillar for the development and applications of molecular biology …

Forensic body fluid identification: state of the art

SA Harbison, RI Fleming - Research and Reports in Forensic …, 2016 - Taylor & Francis
Body fluid identification is a key component in the forensic scientists' tool box and has been
carried out both at the crime scene and in the laboratory for many years. Historically …

A prospective study of environmental exposures and early biomarkers in autism spectrum disorder: design, protocols, and preliminary data from the MARBLES study

I Hertz-Picciotto, RJ Schmidt, CK Walker… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: Until recently, environmental factors in autism spectrum disorder (ASD) were
largely ignored. Over the last decade, altered risks from lifestyle, medical, chemical, and …

Sex-specific DNA methylation: impact on human health and development

P Govender, M Ghai, M Okpeku - Molecular Genetics and Genomics, 2022 - Springer
Human evolution has shaped gender differences between males and females. Over the
years, scientific studies have proposed that epigenetic modifications significantly influence …

[HTML][HTML] Chronological age prediction based on DNA methylation: massive parallel sequencing and random forest regression

J Naue, HCJ Hoefsloot, ORF Mook… - Forensic science …, 2017 - Elsevier
The use of DNA methylation (DNAm) to obtain additional information in forensic
investigations showed to be a promising and increasing field of interest. Prediction of the …

DNA methylation-based variation between human populations

F Kader, M Ghai - Molecular genetics and genomics, 2017 - Springer
Several studies have proved that DNA methylation affects regulation of gene expression and
development. Epigenome-wide studies have reported variation in methylation patterns …

Proof of concept study of age-dependent DNA methylation markers across different tissues by massive parallel sequencing

J Naue, T Sänger, HCJ Hoefsloot… - Forensic Science …, 2018 - Elsevier
The use of DNA methylation (DNAm) for chronological age determination has been widely
investigated within the last few years for its application within the field of forensic genetics …