[HTML][HTML] Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities
Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …
Reinventing radiobiology in the light of FLASH radiotherapy
Ultrahigh–dose rate FLASH radiotherapy (FLASH-RT) is a potentially paradigm-shifting
treatment modality that holds the promise of expanding the therapeutic index for nearly any …
treatment modality that holds the promise of expanding the therapeutic index for nearly any …
An inflammation-centric view of neurological disease: beyond the neuron
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders
The endocannabinoid system (ECS) is composed of two G protein-coupled receptors
(GPCRs), the cannabinoid CB1 and CB2 receptors, and the two main endogenous lipid …
(GPCRs), the cannabinoid CB1 and CB2 receptors, and the two main endogenous lipid …
The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations
S Petrosino, V Di Marzo - British journal of pharmacology, 2017 - Wiley Online Library
Palmitoylethanolamide (PEA) has emerged as a potential nutraceutical, because this
compound is naturally produced in many plant and animal food sources, as well as in cells …
compound is naturally produced in many plant and animal food sources, as well as in cells …
Endocannabinoids and related N-acylethanolamines: biological activities and metabolism
K Tsuboi, T Uyama, Y Okamoto, N Ueda - Inflammation and Regeneration, 2018 - Springer
The plant Cannabis sativa contains cannabinoids represented by Δ 9-tetrahydrocannabinol,
which exert psychoactivity and immunomodulation through cannabinoid CB1 and CB2 …
which exert psychoactivity and immunomodulation through cannabinoid CB1 and CB2 …
Effects of cannabinoids and cannabinoid‐enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes
BACKGROUND AND PURPOSE Cannabidiol (CBD) and Δ9‐tetrahydrocannabinol (THC)
interact with transient receptor potential (TRP) channels and enzymes of the …
interact with transient receptor potential (TRP) channels and enzymes of the …
Peroxisome proliferator-activated receptors: Experimental targeting for the treatment of inflammatory bowel diseases
The peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor
proteins that promote ligand-dependent transcription of target genes that regulate energy …
proteins that promote ligand-dependent transcription of target genes that regulate energy …
The concise guide to PHARMACOLOGY 2013/14: enzymes
SPH Alexander, HE Benson… - British Journal of …, 2013 - Wiley Online Library
Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …
Mast cells, glia and neuroinflammation: partners in crime?
SD Skaper, L Facci, P Giusti - Immunology, 2014 - Wiley Online Library
Glia and microglia in particular elaborate pro‐inflammatory molecules that play key roles in
central nervous system (CNS) disorders from neuropathic pain and epilepsy to …
central nervous system (CNS) disorders from neuropathic pain and epilepsy to …