Pathology, target discovery, and the evolution of XO inhibitors from the first discovery to recent advances (2020–2023)

N Kumar, K Kaur, N Kaur, E Singh, PMS Bedi - Bioorganic Chemistry, 2024 - Elsevier
Hyperuricemia, a disease characterized by elevation of serum uric acid level beyond 6
mg/dL. This elevation led to appearance of symptoms from joint pain to gout and from gout to …

Recent advances on natural depsidones: Sources, biosynthesis, structure-activity relationship, and bioactivities

MT Khayat, KF Ghazawi, WA Samman, AA Alhaddad… - PeerJ, 2023 - peerj.com
Depsidones are a class of polyphenolic polyketides that have been proposed to be
biosynthesized from oxidative coupling of esters of two polyketidic benzoic acid derivatives …

Salazinic acid attenuates male sexual dysfunction and testicular oxidative damage in streptozotocin-induced diabetic albino rats

KN Killari, H Polimati, D Prasanth, G Singh, SP Panda… - RSC …, 2023 - pubs.rsc.org
Male sexual dysfunctions such as infertility and impotence are recognized as the
consequences of diabetes. Salazinic acid (Sa) is a depsidone found in lichen genera of …

Lobaric acid prevents the adverse effects of tetramethrin on the estrous cycle of female albino Wistar rats

HT Nguyen, H Polimati, SSP Annam, E Okello… - Plos one, 2022 - journals.plos.org
Tetramethrin (Tm) is a commonly used pesticide that has been reported to exert estrogen-
antagonistic effects selectively on female rats. The present study was undertaken to assess …

Phylogenetic Studies and Metabolite Analysis of Sticta Species from Colombia and Chile by Ultra-High Performance Liquid Chromatography-High Resolution-Q …

L Albornoz, A Torres-Benítez, M Moreno-Palacios… - Metabolites, 2022 - mdpi.com
Eleven species of lichens of the genus Sticta, ten of which were collected in Colombia (S.
pseudosylvatica S. luteocyphellata S. cf. andina S. cf. hypoglabra, S. cordillerana, S. cf …

Dibenzofurans from Cladonia corniculata Ahti and Kashiw inhibit key enzymes involved in inflammation and gout: An in vitro approach

VK Tatipamula, VB Tatipamula - 2021 - nopr.niscpr.res.in
The usage of natural sources like lichen extracts and their metabolites as anti-inflammatory
agents is well known for ages. Based on the data of the folklore and documented books …

[PDF][PDF] Hepatoprotective Properties of Starflowers from an Annual Herb, Borago officinalis L.(Boraginaceae): Hepatoprotective profile of Borage

SS Manthena, H Polimati, SSP Annam… - International …, 2022 - journals.sbmu.ac.ir
Traditionally, the decoction of leaves, flowers and stems of Borago officinalis was widely
used in the treatment of liver diseases. The present work is aimed to assess the …

Impact of Antioxidant rich fractions isolated from moss Fissidens grandiflora on alcohol-induced oxidative stress

M Meka, N Panatula, SK Nemala… - Research Journal of …, 2022 - indianjournals.com
The present study is aimed to evaluate the antioxidant and hepatoprotective properties of
selected ethanolic fractions of Fissidens grandiflora in ethanol-induced oxidative stress in …