GelMA-based bioactive hydrogel scaffolds with multiple bone defect repair functions: therapeutic strategies and recent advances
B Zhou, X Jiang, X Zhou, W Tan, H Luo, S Lei… - Biomaterials …, 2023 - spj.science.org
Currently, the clinical treatment of critical bone defects attributed to various causes remains
a great challenge, and repairing these defects with synthetic bone substitutes is the most …
a great challenge, and repairing these defects with synthetic bone substitutes is the most …
Leveraging the recent advancements in GelMA scaffolds for bone tissue engineering: an assessment of challenges and opportunities
The field of bone tissue engineering has seen significant advancements in recent years.
Each year, over two million bone transplants are performed globally, and conventional …
Each year, over two million bone transplants are performed globally, and conventional …
Diabetic bone regeneration with nanoceria-tailored scaffolds by recapitulating cellular microenvironment: activating integrin/TGF-β co-signaling of MSCs while …
Regenerating defective bone in patients with diabetes mellitus remains a significant
challenge due to high blood glucose level and oxidative stress. Here we aim to tackle this …
challenge due to high blood glucose level and oxidative stress. Here we aim to tackle this …
Multifunctional molybdenum-based nanoclusters engineered gelatin methacryloyl as in situ photo-cross-linkable hybrid hydrogel dressings for enhanced wound …
Skin injuries and wounds present significant clinical challenges, necessitating the
development of advanced wound dressings for efficient wound healing and tissue …
development of advanced wound dressings for efficient wound healing and tissue …
Nanozyme-Engineered Hydrogels for Anti-Inflammation and Skin Regeneration
Inflammatory skin disorders can cause chronic scarring and functional impairments, posing
a significant burden on patients and the healthcare system. Conventional therapies, such as …
a significant burden on patients and the healthcare system. Conventional therapies, such as …
GelMA and biomimetic culture allow the engineering of mineralized, adipose, and tumor tissue human microenvironments for the study of advanced prostate cancer in …
Increasing evidence shows bone marrow (BM)‐adipocytes as a potentially important
contributor in prostate cancer (PCa) bone metastases. However, a lack of relevant models …
contributor in prostate cancer (PCa) bone metastases. However, a lack of relevant models …
[HTML][HTML] Multifunctional dendrimer@ nanoceria engineered GelMA hydrogel accelerates bone regeneration through orchestrated cellular responses
Bone defects in patients entail the microenvironment that needs to boost the functions of
stem cells (eg, proliferation, migration, and differentiation) while alleviating severe …
stem cells (eg, proliferation, migration, and differentiation) while alleviating severe …
Roles of neutrophil reactive oxygen species (ROS) generation in organ function impairment in sepsis
J Lu, J Liu, A Li - Journal of Zhejiang University-SCIENCE B, 2022 - Springer
Sepsis is a condition of severe organ failure caused by the maladaptive response of the host
to an infection. It is a severe complication affecting critically ill patients, which can progress …
to an infection. It is a severe complication affecting critically ill patients, which can progress …
Nanoceria-GO-intercalated multicellular spheroids revascularize and salvage critical ischemic limbs through anti-apoptotic and pro-angiogenic functions
Critical limb ischemia (CLI) is a serious form of peripheral arterial disease that involves
severe blockage of blood flow in lower extremities, often leading to foot necrosis and limb …
severe blockage of blood flow in lower extremities, often leading to foot necrosis and limb …
Mussel-inspired surface functionalization of porous albumin cryogels supporting synergistic antibacterial/antioxidant activity and bone-like apatite formation
A crucial method for adding new functions to current biomaterials for biomedical applications
has been surface functionalization via molecular design. Mussel-inspired polydopamine …
has been surface functionalization via molecular design. Mussel-inspired polydopamine …