Infectious diseases, along with cancers, are among the main causes of death among
humans worldwide. The production of therapeutic proteins for treating diseases at large …

Membrane systems play an essential role in the production of all biopharmaceuticals. This
includes initial clarification of cell culture fluid by both depth filtration and tangential flow …

Therapeutic antibody technology heavily dominates the biologics market and continues to
present as a significant industrial interest in develo** novel and improved antibody …

Continuous crystallization has been proposed as the downstream processing step for the
purification of pharmaceutical proteins aimed at alleviating the manufacturing bottleneck …

Over the last few years rapid progress has been made in adopting well‐known process
modeling techniques from chemicals to biologics manufacturing. The main challenge has …

The biopharmaceutical industry has an ongoing interest in improving manufacturing
efficiency and productivity while at the same time reducing manufacturing costs by …

Chinese hamster ovary (CHO) cells are the predominant host cell line for the production of
biopharmaceuticals, a growing industry currently worth more than $188 billion USD in global …

The demand on biologics has been constantly rising over the past decades and has become
crucial in modern medicine. Promising approaches to cope with widespread diseases like …

Downstream processing is considered one of the most challenging phases of industrial
manufacturing of therapeutic proteins, accounting for a large portion of the total production …

The need to intensify downstream processing of monoclonal antibodies to complement the
advances in upstream productivity has led to increased attention toward implementing …