The current landscape of bioactive molecules against DENV: A systematic review

R Babbar, R Kaur, P Rana, S Arora… - Evidence‐Based …, 2023 - Wiley Online Library
With a 30‐fold increase in incidence over the previous 50 years, dengue fever is now the
most widespread viral disease transmitted by mosquitoes in the world. The intricate …

Molecular Design and In‐Silico Analysis of Trisubstituted Benzimidazole Derivatives as Ftsz Inhibitor

S Thapa, SL Nargund, MS Biradar - Journal of Chemistry, 2023 - Wiley Online Library
Tuberculosis (TB) is the fastest spreading infectious disease and one of the top ten diseases
that kill millions of people annually. The rapid spread of a multidrug‐resistant strain of …

Computational evaluation of quinones of Nigella sativa L. as potential inhibitor of dengue virus NS5 methyltransferase

M Roney, A Dubey, MH Nasir, AM Huq… - Journal of …, 2024 - Taylor & Francis
Aedes aegypti is the primary vector for the transmission of the dengue virus, which causes
dengue fever, dengue hemorrhagic illness and dengue shock syndrome. There is now no …

Pharmacophore-based virtual screening and in-silico study of natural products as potential DENV-2 RdRp inhibitors

M Roney, AKMM Huq, AR Issahaku… - Journal of …, 2023 - Taylor & Francis
Dengue fever is a significant public health concern throughout the world, causing an
estimated 500,000 hospitalizations and 20,000 deaths each year, despite the lack of …

[HTML][HTML] Molecular docking interaction of bioactive molecules from Kigelia africana (lam.) benth., revealed potential inhibitors of penicillin-binding protein 2 (PBP2)

P Manogar, SV Prabhu, P Durairaj, MMJ Abel… - Aspects of Molecular …, 2024 - Elsevier
One million men, women and children are affected by sexually transmitted infections (STIs),
which are a leading cause of sudden illness, sterility, long-term disability and mortality with …

Preliminary Evaluation of Lablab purpureus Phytochemicals for Anti-BoHV-1 Activity Using In Vitro and In Silico Approaches

SS Bhat, S Pradeep, SS Patil, N Flores-Holguín… - ACS …, 2023 - ACS Publications
Lablab purpureus from the Fabaceae family has been reported to have antiviral properties
and used in traditional medical systems like ayurveda and Chinese medicine and has been …

Selected phytochemicals of Momordica charantia L. as potential anti-DENV-2 through the docking, DFT and molecular dynamic simulation

AKMM Huq, M Roney, AR Issahaku… - Journal of …, 2024 - Taylor & Francis
Dengue fever is now one of the major global health concerns particularly for tropical and sub-
tropical countries. However, there has been no FDA approved medication to treat dengue …

Molecular docking and dynamics simulation reveal withanolides as potent antivirals against dengue virus

MF Lee, SL Tan, N Ahemad, AAA Hamid… - South African Journal of …, 2024 - Elsevier
The prevalence of dengue remains a significant global threat to public health with millions of
infections reported annually due to the lack of effective treatment options. Natural resources …

Investigating natural plant products as potential inhibitors to disrupt NS1 β-roll domain polymerisation in DENV2: a detailed computational chemistry approach

T Paul, A Roy, I Paul, P Banerjee, S Ray - Molecular Simulation, 2024 - Taylor & Francis
The aim of this investigation is to design a novel drug, screened through various
computational methods, that harnesses the historical evidence of plant products inhibiting …

Computational Advancement towards the Identification of Natural Inhibitors for Dengue Virus: A Brief Review

M Sajid, I Tur Razia, A Kanwal, M Ahsan… - … Chemistry & High …, 2024 - benthamdirect.com
Viral infectious illnesses represent a severe hazard to human health due to their widespread
incidence worldwide. Among these ailments, the dengue virus (DENV) infection stands out …