Nivolumab plus ipilimumab with or without live bacterial supplementation in metastatic renal cell carcinoma: a randomized phase 1 trial

N Dizman, L Meza, P Bergerot, M Alcantara, T Dorff… - Nature medicine, 2022 - nature.com
Previous studies have suggested that the gut microbiome influences the response to
checkpoint inhibitors (CPIs) in patients with cancer. CBM588 is a bifidogenic live bacterial …

[HTML][HTML] Commensal bacteria and fungi differentially regulate tumor responses to radiation therapy

SL Shiao, KM Kershaw, JJ Limon, S You, J Yoon… - Cancer cell, 2021 - cell.com
Studies suggest that the efficacy of cancer chemotherapy and immunotherapy is influenced
by intestinal bacteria. However, the influence of the microbiome on radiation therapy is not …

The intratumor mycobiome promotes lung cancer progression via myeloid-derived suppressor cells

NN Liu, CX Yi, LQ Wei, JA Zhou, T Jiang, CC Hu… - Cancer Cell, 2023 - cell.com
Although polymorphic microbiomes have emerged as hallmarks of cancer, far less is known
about the role of the intratumor mycobiome as living microorganisms in cancer progression …

[HTML][HTML] Multi-template polymerase chain reaction

E Kalle, M Kubista, C Rensing - Biomolecular Detection and Quantification, 2014 - Elsevier
PCR is a formidable and potent technology that serves as an indispensable tool in a wide
range of biological disciplines. However, due to the ease of use and often lack of rigorous …

The mammalian mycobiome: a complex system in a dynamic relationship with the host

GC Lai, TG Tan, N Pavelka - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Mammalian barrier surfaces are densely populated by symbiont fungi in much the same way
the former are colonized by symbiont bacteria. The fungal microbiota, otherwise known as …

High-resolution mycobiota analysis reveals dynamic intestinal translocation preceding invasive candidiasis

B Zhai, M Ola, T Rolling, NL Tosini, S Joshowitz… - Nature medicine, 2020 - nature.com
The intestinal microbiota is a complex community of bacteria, archaea, viruses, protists and
fungi,. Although the composition of bacterial constituents has been linked to immune …

Intestinal fungi contribute to development of alcoholic liver disease

AM Yang, T Inamine, K Hochrath… - The Journal of …, 2017 - Am Soc Clin Investig
Chronic liver disease with cirrhosis is the 12th leading cause of death in the United States,
and alcoholic liver disease accounts for approximately half of all cirrhosis deaths. Chronic …

Immunological consequences of intestinal fungal dysbiosis

ML Wheeler, JJ Limon, AS Bar, CA Leal, M Gargus… - Cell host & …, 2016 - cell.com
Compared to bacteria, the role of fungi within the intestinal microbiota is poorly understood.
In this study we investigated whether the presence of a" healthy" fungal community in the gut …

Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection

T Zuo, SH Wong, CP Cheung, K Lam, R Lui… - Nature …, 2018 - nature.com
Fecal microbiota transplantation (FMT) is effective in treating recurrent Clostridium difficile
infection (CDI). Bacterial colonization in recipients after FMT has been studied, but little is …

The Candida albicans exotoxin candidalysin promotes alcohol-associated liver disease

H Chu, Y Duan, S Lang, L Jiang, Y Wang… - Journal of …, 2020 - Elsevier
Background & Aims Alcohol-associated liver disease is a leading indication for liver
transplantation and a leading cause of mortality. Alterations to the gut microbiota contribute …