In this study, analysis of changes of SARS-CoV-2 ORF3a protein during pandemic is
reported. ORF3a, a conserved coronavirus protein, is involved in virus replication and …

The B6 vitamer pyridoxal 5′-phosphate (PLP) is a co-factor for proteins and enzymes that
are involved in diverse cellular processes. Therefore, PLP is essential for organisms from all …

Many biological functions played by current proteins were not created by evolution from
scratch, rather they were obtained combining already available protein scaffolds. This is the …

Abstract Polycystic Ovarian Syndrome (PCOS) is a multifaceted metabolic and hormonal
condition that impacts women in their procreative ages, identified by ovarian dysfunction …

Borrelial pathogens are vector-borne etiological agents known to cause Lyme disease,
relapsing fever, and Borrelia miyamotoi disease. These spirochetes each encode several …

Specificity in protein–DNA recognition arises from the synergy of several factors that stem
from the structural and chemical signatures encoded within the targeted DNA molecule …

Antimicrobial resistance is a significant cause of mortality globally due to infections, a trend
that is expected to continue to rise. As existing treatments fail and new drug discovery slows …

Bacillus subtilis is able to use γ‐aminobutyric acid (GABA) found in the soil as carbon and
nitrogen source, through the action of GABA aminotransferase (GabT) and succinic …

GabR from Bacillus subtilis is a transcriptional regulator of the MocR subfamily of GntR
regulators. The MocR architecture is characterized by the presence of an N-terminal winged …

The mce1 operon of Mycobacterium tuberculosis, important for lipid metabolism/transport,
host cell invasion, modulation of host immune response and pathogenicity, is under the …