Modeling neurodegenerative disorders in zebrafish

AA Bashirzade, KN Zabegalov, AD Volgin… - Neuroscience & …, 2022 - Elsevier
Neurodegeneration is a major cause of Alzheimer's, Parkinson's, Huntington's, multiple and
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …

Acrylamide in food: Occurrence, metabolism, molecular toxicity mechanism and detoxification by phytochemicals

F Yan, L Wang, L Zhao, C Wang, Q Lu, R Liu - Food and Chemical …, 2023 - Elsevier
Acrylamide (ACR) is a common pollutant formed during food thermal processing such as
frying, baking and roasting. ACR and its metabolites can cause various negative effects on …

5-O-Demethylnobiletin Alleviates CCl4-Induced Acute Liver Injury by Equilibrating ROS-Mediated Apoptosis and Autophagy Induction

SN Chang, SH Kim, DK Dey, SM Park, O Nasif… - International journal of …, 2021 - mdpi.com
Polymethoxyflavanoids (PMFs) have exhibited a vast array of therapeutic biological
properties. 5-O-Demethylnobiletin (5-DN) is one such PMF having anti-inflammatory activity …

Polystyrene microplastics modulated bdnf expression triggering neurotoxicity via apoptotic pathway in zebrafish embryos

A Suman, A Mahapatra, P Gupta, SS Ray… - … and Physiology Part C …, 2023 - Elsevier
A ubiquitous presence of microplastics and nanoplastics created a new toxicological
research area arising concept of “plastic rivers”. But, the precise molecular mechanisms by …

Unveiling the impact of Aging on BBB and Alzheimer's disease: Factors and Therapeutic implications

VK Nelson, NK Jha, MV Nuli, S Gupta, S Kanna… - Ageing research …, 2024 - Elsevier
Alzheimer's disease (AD) is a highly prevalent neurodegenerative condition that has
devastating effects on individuals, often resulting in dementia. AD is primarily defined by the …

Recent development in zebrafish model for bioactivity and safety evaluation of natural products

FJ Lin, H Li, DT Wu, QG Zhuang, HB Li… - Critical Reviews in …, 2022 - Taylor & Francis
The zebrafish is a species of freshwater fish, popular in aquariums and laboratories. Several
advantageous features have facilitated zebrafish to be extensively utilized as a valuable …

[HTML][HTML] The potential roles of ATF family in the treatment of Alzheimer's disease

T Yang, Y Zhang, L Chen, ER Thomas, W Yu… - Biomedicine & …, 2023 - Elsevier
Activating transcription factors, ATFs, is a family of transcription factors that activate gene
expression and transcription by recognizing and combining the cAMP response element …

Acrylamide toxicity in aquatic animals and its mitigation approaches: an updated overview

MAE Naiel, SS Negm, S Ghazanfar, A Farid… - … Science and Pollution …, 2023 - Springer
Acrylamide (ACR) is widely applied in various industrial activities, as well as in the water
purification process. Furthermore, ACR is synthesized naturally in some starchy grains …

Role of macrophages and microglia in zebrafish regeneration

SR Var, CA Byrd-Jacobs - International journal of molecular sciences, 2020 - mdpi.com
Currently, there is no treatment for recovery of human nerve function after damage to the
central nervous system (CNS), and there are limited regenerative capabilities in the …

Effect of aerobic exercise as a treatment on type 2 diabetes mellitus with depression-like behavior zebrafish

L Wang, J Ma, W Wu, Y Fang, F Liu, Q Yang, X Hu… - Life Sciences, 2022 - Elsevier
Background Depression is the most known complication of type 2 diabetes mellitus (T2DM).
Aerobic exercise improves glycemic control in T2DM, although the underlying mechanisms …