Motor deficits typical of Parkinson's disease (PD), such as gait and balance disturbances,
tremor, reduced arm swing and finger movement, and voice and breathing changes, are …

Alzheimer's disease (AD) and other neurodegenerative diseases such as Parkinson's
disease (PD) and Huntington's disease (HD) are associated with progressive cognitive …

Multiple sclerosis (MS) is a neurological disease of the central nervous system that is the
leading cause of non-traumatic disability in young adults. Clinical laboratory tests and …

The field of psychoneuroimmunology (PNI) has grown substantially in both relevance and
prominence over the past 40 years. Notwithstanding its impressive trajectory, a majority of …

Fatigue is prevalent in immune-mediated inflammatory and neurodegenerative diseases, yet
its assessment relies largely on patient-reported outcomes, which capture perception but not …

Background: Fatigue is a prominent symptom in many diseases and is strongly associated
with impaired daily function. The measurement of daily function is currently almost always …

Background: Innovative Medicines Initiative (IMI) consortium IDEA-FAST is develo** novel
digital measures of fatigue, sleep quality, and impact of sleep disturbances for …

Remote inflammation monitoring with digital health technologies (DHTs) would provide
valuable information for both clinical research and care. Controlled perturbations of the …

Wearables with photoplethysmography (PPG) sensors are being increasingly used in
clinical research as a non-invasive, inexpensive method for remote monitoring of …

Digital measures can provide quantitative assessment of a range of disease-specific
impairments, including motor, speech, cognition and physiological functioning. People with …