Regulatory activities of transposable elements: from conflicts to benefits
Transposable elements (TEs) are a prolific source of tightly regulated, biochemically active
non-coding elements, such as transcription factor-binding sites and non-coding RNAs. Many …
non-coding elements, such as transcription factor-binding sites and non-coding RNAs. Many …
Widespread sex dimorphism in aging and age-related diseases
NK Sampathkumar, JI Bravo, Y Chen, PS Danthi… - Human genetics, 2020 - Springer
Although aging is a conserved phenomenon across evolutionary distant species, aspects of
the aging process have been found to differ between males and females of the same …
the aging process have been found to differ between males and females of the same …
The majority of primate-specific regulatory sequences are derived from transposable elements
Although emerging evidence suggests that transposable elements (TEs) have contributed
novel regulatory elements to the human genome, their global impact on transcriptional …
novel regulatory elements to the human genome, their global impact on transcriptional …
Retrotransposons in plant genomes: structure, identification, and classification through bioinformatics and machine learning
Transposable elements (TEs) are genomic units able to move within the genome of virtually
all organisms. Due to their natural repetitive numbers and their high structural diversity, the …
all organisms. Due to their natural repetitive numbers and their high structural diversity, the …
Role of transposable elements in gene regulation in the human genome
Transposable elements (TEs), also known as mobile elements (MEs), are interspersed
repeats that constitute a major fraction of the genomes of higher organisms. As one of their …
repeats that constitute a major fraction of the genomes of higher organisms. As one of their …
Large-scale long terminal repeat insertions produced a significant set of novel transcripts in cotton
Y Yang, X Wen, Z Wu, K Wang, Y Zhu - Science China Life Sciences, 2023 - Springer
Genomic analysis has revealed that the 1,637-Mb Gossypium arboreum genome contains
approximately 81% transposable elements (TEs), while only 57% of the 735-Mb G. raimondii …
approximately 81% transposable elements (TEs), while only 57% of the 735-Mb G. raimondii …
Genome-wide activity of unliganded estrogen receptor-α in breast cancer cells
Estrogen receptor-α (ERα) has central role in hormone-dependent breast cancer and its
ligand-induced functions have been extensively characterized. However, evidence exists …
ligand-induced functions have been extensively characterized. However, evidence exists …
Transposons: Unexpected players in cancer
RK Pradhan, W Ramakrishna - Gene, 2022 - Elsevier
Transposons are repetitive DNA sequences encompassing about half of the human
genome. They play a vital role in genome stability maintenance and contribute to genomic …
genome. They play a vital role in genome stability maintenance and contribute to genomic …
Identification of novel cattle (Bos taurus) genes and biological insights of their function in pre-implantation embryo development
GP Schettini, M Morozyuk, FH Biase - BMC genomics, 2024 - Springer
Background Appropriate regulation of genes expressed in oocytes and embryos is essential
for acquisition of developmental competence in mammals. Here, we hypothesized that …
for acquisition of developmental competence in mammals. Here, we hypothesized that …
Extensive amplification of the E2F transcription factor binding sites by transposons during evolution of Brassica species
Transposable elements (TE s) are major players in genome evolution. The effects of their
movement vary from gene knockouts to more subtle effects such as changes in gene …
movement vary from gene knockouts to more subtle effects such as changes in gene …