[HTML][HTML] Differential gene expression analysis pipelines and bioinformatic tools for the identification of specific biomarkers: a review

D Rosati, M Palmieri, G Brunelli, A Morrione… - Computational and …, 2024 - Elsevier
In recent years, the role of bioinformatics and computational biology together with omics
techniques and transcriptomics has gained tremendous importance in biomedicine and …

Multimodal AI/ML for discovering novel biomarkers and predicting disease using multi-omics profiles of patients with cardiovascular diseases

W DeGroat, H Abdelhalim, E Peker, N Sheth… - Scientific Reports, 2024 - nature.com
Cardiovascular diseases (CVDs) are complex, multifactorial conditions that require
personalized assessment and treatment. Advancements in multi-omics technologies …

Identified S100A9 as a target for diagnosis and treatment of ulcerative colitis by bioinformatics analysis

L Tan, X Li, H Qin, Q Zhang, J Wang, T Chen… - Scientific Reports, 2024 - nature.com
Ulcerative colitis (UC) is a chronic, recurrent inflammatory bowel disease. UC confronts with
severe challenges including the unclear pathogenesis and lack of specific diagnostic …

Bioinformatics and next-generation data analysis for identification of genes and molecular pathways involved in subjects with diabetes and obesity

P Ganekal, B Vastrad, S Kavatagimath, C Vastrad… - Medicina, 2023 - mdpi.com
Background and Objectives: A subject with diabetes and obesity is a class of the metabolic
disorder. The current investigation aimed to elucidate the potential biomarker and prognostic …

Functional deficiency of succinate dehydrogenase promotes tumorigenesis and development of clear cell renal cell carcinoma through weakening of ferroptosis

J Yang, Y Zhou, Y Li, W Hu, C Yuan, S Chen, G Ye… - …, 2022 - Taylor & Francis
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal carcinomas,
with high mortality and poor prognoses worldwide. Succinate dehydrogenase (SDH) …

Transcriptional profiling and deriving a seven-gene signature that discriminates active and latent tuberculosis: an integrative bioinformatics approach

S Natarajan, M Ranganathan, LE Hanna, S Tripathy - Genes, 2022 - mdpi.com
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (M. tb.).
Our integrative analysis aims to identify the transcriptional profiling and gene expression …

A multifunctional injectable, self-healing, and adhesive hydrogel-based wound dressing stimulated diabetic wound healing with combined reactive oxygen species …

R Chen, P Wang, J ** of protective immunity genes against SARS-CoV-2 …
C Chakraborty, AR Sharma, M Bhattacharya… - Frontiers in …, 2021 - frontiersin.org
The COVID-19 pandemic has created an urgent situation throughout the globe. Therefore, it
is necessary to identify the differentially expressed genes (DEGs) in COVID-19 patients to …

Integrative weighted molecular network construction from transcriptomics and genome wide association data to identify shared genetic biomarkers for COPD and lung …

B Banaganapalli, B Mallah, KS Alghamdi… - Plos one, 2022 - journals.plos.org
Chronic obstructive pulmonary disease (COPD) is a multifactorial progressive airflow
obstruction in the lungs, accounting for high morbidity and mortality across the world. This …