Clinical implications of the intrinsic molecular subtypes of breast cancer
Gene-expression profiling has had a considerable impact on our understanding of breast
cancer biology. During the last 15 years, 5 intrinsic molecular subtypes of breast cancer …
cancer biology. During the last 15 years, 5 intrinsic molecular subtypes of breast cancer …
Luminal B breast cancer: molecular characterization, clinical management, and future perspectives
F Ades, D Zardavas, I Bozovic-Spasojevic… - Journal of clinical …, 2014 - ascopubs.org
Gene expression profiling has reshaped our understanding of breast cancer by defining and
characterizing four main intrinsic molecular subtypes: human epidermal growth factor …
characterizing four main intrinsic molecular subtypes: human epidermal growth factor …
Breast cancer, version 3.2024, NCCN clinical practice guidelines in oncology
WJ Gradishar, MS Moran, J Abraham… - Journal of the National …, 2024 - jnccn.org
Breast cancer is treated with a multidisciplinary approach involving surgical oncology,
radiation oncology, and medical oncology. The NCCN Clinical Practice Guidelines in …
radiation oncology, and medical oncology. The NCCN Clinical Practice Guidelines in …
Assessment of Ki67 in breast cancer: recommendations from the International Ki67 in Breast Cancer working group
M Dowsett, TO Nielsen, R A'Hern… - Journal of the …, 2011 - academic.oup.com
Uncontrolled proliferation is a hallmark of cancer. In breast cancer, immunohistochemical
assessment of the proportion of cells staining for the nuclear antigen Ki67 has become the …
assessment of the proportion of cells staining for the nuclear antigen Ki67 has become the …
Long-term outcome and prognostic value of Ki67 after perioperative endocrine therapy in postmenopausal women with hormone-sensitive early breast cancer …
I Smith, J Robertson, L Kilburn, M Wilcox… - The Lancet …, 2020 - thelancet.com
Background Preoperative and perioperative aromatase inhibitor (POAI) therapy has the
potential to improve outcomes in women with operable oestrogen receptor-positive primary …
potential to improve outcomes in women with operable oestrogen receptor-positive primary …
Whole-genome analysis informs breast cancer response to aromatase inhibition
To correlate the variable clinical features of oestrogen-receptor-positive breast cancer with
somatic alterations, we studied pretreatment tumour biopsies accrued from patients in two …
somatic alterations, we studied pretreatment tumour biopsies accrued from patients in two …
Prognostic significance of progesterone receptor–positive tumor cells within immunohistochemically defined luminal A breast cancer
Purpose Current immunohistochemical (IHC)-based definitions of luminal A and B breast
cancers are imperfect when compared with multigene expression-based assays. In this …
cancers are imperfect when compared with multigene expression-based assays. In this …
Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts
To characterize patient-derived xenografts (PDXs) for functional studies, we made whole-
genome comparisons with originating breast cancers representative of the major intrinsic …
genome comparisons with originating breast cancers representative of the major intrinsic …
An international Ki67 reproducibility study
Background In breast cancer, immunohistochemical assessment of proliferation using the
marker Ki67 has potential use in both research and clinical management. However, lack of …
marker Ki67 has potential use in both research and clinical management. However, lack of …
[HTML][HTML] ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2)
Author links open overlay panel F. Cardoso a, A. Costa bc, L. Norton d, E. Senkus e, M.
Aapro f, F. André g, CH Barrios h, J. Bergh i, L. Biganzoli j, KL Blackwell k, MJ Cardoso l, T …
Aapro f, F. André g, CH Barrios h, J. Bergh i, L. Biganzoli j, KL Blackwell k, MJ Cardoso l, T …