In recent years, the role of gut microbial metabolites on the inhibition and progression of
cancer has gained significant interest in anticancer research. It has been established that …

The complex association between the gut microbiome and cancer development has been
an emerging field of study in recent years. The gut microbiome plays a crucial role in the …

Peptide–drug conjugates are organic molecules composed of (i) a small drug molecule,(ii) a
peptide and (iii) a linker. The drug molecule is mandatory for the biological action, however …

Receptors for gonadotropin releasing hormone (GnRH) are highly expressed in various
human cancers including breast, ovarian, endometrial, prostate and colorectal cancer …

Fungal endophytes are remarkable sources of biologically active metabolites of ecological
and pharmacological significance. In this study, fungal isolates producing yellow pigments …

Tamoxifen is a long-known anti-tumor drug, which is the gold standard therapy in estrogen
receptor (ER) positive breast cancer patients. According to previous studies, the conjugation …

Background Gonadotropin-releasing hormone receptor (GnRHR) is expressed in several
malignant tumors and inhibits the proliferation and metastasis of cancer cells, but its role in …

By means of copper (I)-and ruthenium (II)-catalyzed click reactions of quinine-and quinidine-
derived alkynes with azide-substituted chalcones a systematic series of novel cinchona …

β-Aminophosphonates obtained by the Michael addition of primary amines to the double
bond of diethyl vinylphosphonate proved to be suitable starting materials (amine …

Four cyclic diarylheptanoids—carpinontriols A (1) and B (2), giffonin X (3) and 3, 12, 17-
trihydroxytricyclo [12.3. 1.12, 6] nonadeca-1 (18), 2 (19), 3, 5, 14, 16-hexaene-8, 11-dione …