Importance of EPA and DHA blood levels in brain structure and function

C von Schacky - Nutrients, 2021 - mdpi.com
Brain structure and function depend on a constant and sufficient supply with
eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) by blood. Blood levels of …

Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 women: results from the European Prevention of …

RNM Saleh, M Hornberger, CW Ritchie… - Alzheimer's research & …, 2023 - Springer
Background The risk of dementia is higher in women than men. The metabolic
consequences of estrogen decline during menopause accelerate neuropathology in …

Therapeutic opportunities for food supplements in neurodegenerative disease and depression

R Businaro, D Vauzour, J Sarris, G Münch… - Frontiers in …, 2021 - frontiersin.org
Emerging evidence is showing nutrition as a crucial factor in the high prevalence and
incidence of neurodegenerative mental disorders. Preventive interventions on …

[HTML][HTML] APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer's disease pathophysiology

TTT Tran, S Corsini, L Kellingray, C Hegarty… - The FASEB …, 2019 - ncbi.nlm.nih.gov
Apolipoprotein E (APOE) genotype is the strongest prevalent genetic risk factor for
Alzheimer's disease (AD). Numerous studies have provided insights into the pathologic …

Altered gut microbiota and its clinical relevance in mild cognitive impairment and Alzheimer's disease: Shanghai Aging Study and Shanghai Memory Study

Z Zhu, X Ma, J Wu, Z **ao, W Wu, S Ding, L Zheng… - Nutrients, 2022 - mdpi.com
Altered gut microbiota has been reported in individuals with mild cognitive impairment (MCI)
and Alzheimer's disease (AD). Previous research has suggested that specific bacterial …

Can nutrition support healthy cognitive ageing and reduce dementia risk?

A Jennings, SC Cunnane, AM Minihane - bmj, 2020 - bmj.com
Can nutrition support healthy cognitive ageing and reduce dementia risk? Page 1 the bmj | BMJ
2020;369:m2269 | doi: 10.1136/bmj.m2269 1 Food For ThoughT 2020 Can nutrition support …

[HTML][HTML] A combined DHA-rich fish oil and cocoa flavanols intervention does not improve cognition or brain structure in older adults with memory complaints: results …

D Vauzour, A Scholey, DJ White, NJ Cohen… - The American journal of …, 2023 - Elsevier
Background There is evidence that both omega-3 long-chain polyunsaturated fatty acids
(PUFAs)(eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) and cocoa …

Hormone therapy is associated with lower Alzheimer's disease tau biomarkers in post-menopausal females-evidence from two independent cohorts

YT Wang, J Therriault, C Tissot, S Servaes… - Alzheimer's Research & …, 2024 - Springer
Background Females represent approximately 70% of the Alzheimer's disease (AD) cases
and the literature has proposed a connection between the decreased estrogen levels during …

APOE4 genotype exacerbates the impact of menopause on cognition and synaptic plasticity in APOE‐TR mice

MG Pontifex, A Martinsen, RNM Saleh… - The FASEB …, 2021 - Wiley Online Library
The impact of sex and menopausal status in Alzheimer's disease remains understudied
despite increasing evidence of greater female risk, particularly in APOE4 carriers. Utilizing …

The role of Foxo3a in neuron-mediated cognitive impairment

QQ Liu, GH Wu, XC Wang, XW **ong… - Frontiers in Molecular …, 2024 - frontiersin.org
Cognitive impairment (COI) is a prevalent complication across a spectrum of brain disorders,
underpinned by intricate mechanisms yet to be fully elucidated. Neurons, the principal cell …