Long non-coding RNAs in genitourinary malignancies: a whole new world

R Flippot, G Beinse, A Boilève, J Vibert… - Nature Reviews …, 2019 - nature.com
Long non-coding RNAs (lncRNAs) are regulators of cellular machinery that are commonly
dysregulated in genitourinary malignancies. Accordingly, the investigation of lncRNAs is …

Identification of CircRNA signature associated with tumor immune infiltration to predict therapeutic efficacy of immunotherapy

Y Dong, Q Gao, Y Chen, Z Zhang, Y Du, Y Liu… - Nature …, 2023 - nature.com
Circular RNAs (circRNAs) play important roles in the regulation of cancer. However, the
clinical implications and regulatory networks of circRNAs in cancer patients receiving …

[HTML][HTML] Immune-related lncRNA to construct novel signature and predict the immune landscape of human hepatocellular carcinoma

W Hong, L Liang, Y Gu, Z Qi, H Qiu, X Yang… - … Therapy-Nucleic Acids, 2020 - cell.com
The signature composed of immune-related long noncoding ribonucleic acids (irlncRNAs)
with no requirement of specific expression level seems to be valuable in predicting the …

[HTML][HTML] Noncoding RNAs in tumorigenesis and tumor therapy

P Zhu, B Liu, Z Fan - Fundamental Research, 2023 - Elsevier
Tumorigenesis is a complicated process in which numerous modulators are involved in
different ways. Previous studies have focused primarily on tumor-associated protein-coding …

An immune cell infiltration-based immune score model predicts prognosis and chemotherapy effects in breast cancer

S Sui, X An, C Xu, Z Li, Y Hua, G Huang, S Sui… - …, 2020 - pmc.ncbi.nlm.nih.gov
Background: Immune cells have essential auxiliary functions and influence clinical
outcomes in cancer, with high immune infiltration being associated with improved clinical …

Prognostic model development for classification of colorectal adenocarcinoma by using machine learning model based on feature selection technique boruta

NS Maurya, S Kushwah, S Kushwaha, A Chawade… - Scientific reports, 2023 - nature.com
Colorectal cancer (CRC) is the third most prevalent cancer type and accounts for nearly one
million deaths worldwide. The CRC mRNA gene expression datasets from TCGA and GEO …

Exosomal AP000439. 2 from clear cell renal cell carcinoma induces M2 macrophage polarization to promote tumor progression through activation of STAT3

T Shen, S Miao, Y Zhou, X Yi, S Xue, B Du… - Cell Communication and …, 2022 - Springer
Background Tumorigenic phenotype of M2 tumor-associated macrophages promote tumor
progression in response to exosomes cues imposed by tumor cells. However, the effect and …

A multi-classifier system integrated by clinico-histology-genomic analysis for predicting recurrence of papillary renal cell carcinoma

KB Huang, CP Gui, YZ Xu, XS Li, HW Zhao… - Nature …, 2024 - nature.com
Integrating genomics and histology for cancer prognosis demonstrates promise. Here, we
develop a multi-classifier system integrating a lncRNA-based classifier, a deep learning …

Identification and verification of an immune-related lncRNA signature for predicting the prognosis of patients with bladder cancer

J Wang, C Shen, D Dong, X Zhong, Y Wang… - International …, 2021 - Elsevier
Background Recent studies have revealed the significant roles of immune-related long
noncoding RNAs (lncRNAs) in cancer development and progression. The identification of …

Circular RNA ABCB10 promotes tumor progression and correlates with pejorative prognosis in clear cell renal cell carcinoma

Y Huang, Y Zhang, L Jia, C Liu… - The International Journal …, 2019 - journals.sagepub.com
Objective: Our study aimed to evaluate the effect of circular RNA ABCB10 (circ-ABCB10) on
proliferation and apoptosis of clear cell renal cell carcinoma (ccRCC) cells, and its …