Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

Reactive oxygen species (ROS) are critical for the progression of cardiovascular diseases,
inflammations and tumors. However, the mechanisms of how ROS sense metabolic stress …

The vascular endothelium is an interface between the blood stream and the vessel wall.
Changes in this single cell layer of the artery wall are believed of primary importance in the …

Arterial stiffness results from a degenerative process affecting mainly the extracellular matrix
of elastic arteries under the effect of aging and risk factors. Changes in extracellular matrix …

Nitric oxide (NO) has been implicated in a variety of physiological and pathological
processes. Monitoring cellular levels of NO requires a sensor to feature adequate sensitivity …

Oxidative stress has long been implicated in cardiovascular disease, but more recently, the
role of reactive oxygen species (ROS) in normal physiological signaling has been …

Oxidative stress has been implicated in the pathophysiology of diabetic nephropathy.
Studies in experimental animal models of diabetes strongly implicate oxidant species as a …

Ultrasound contrast agents are valuable in diagnostic ultrasound imaging, and they
increasingly show potential for drug delivery. This review focuses on the acoustic behavior …

Vascular endothelial cells are subjected to hemodynamic forces such as mechanical stretch
due to the pulsatile nature of blood flow. Mechanical stretch of different intensities is …

Reactive oxygen species, particularly superoxide, promote endothelial dysfunction and
alterations in vascular structure. It is increasingly recognized that inflammatory cytokines …