Epithelial ovarian cancer (OvCa) is associated with high mortality and, as the majority (>
75%) of women with OvCa have metastatic disease at the time of diagnosis, rates of survival …

The solute carrier (SLC) family 10 (SLC10) comprises influx transporters of bile acids,
steroidal hormones, various drugs, and several other substrates. Because the seminal …

Osteosarcoma is the most common malignant bone tumor in children and adolescence.
Multiple immune-related genes have been reported in different cancers. The aim is to …

The human fallopian tube harbors the cell of origin for the majority of high-grade serous"
ovarian" cancers (HGSCs), but its cellular composition, particularly the epithelial component …

Objectives The purpose of this study was to determine the level of heterogeneity in high
grade serous ovarian cancer (HGSOC) by analyzing RNA expression in single epithelial …

LAT1 is a member of the system L transporter family. The main role of the LAT1 is to
transport specific amino acids through cell membranes to provide nutrients to cells and …

The mitochondrion relies on compartmentalization of certain enzymes, ions and metabolites
for the sake of efficient metabolism. In order to fulfil its activities, a myriad of carriers are …

Reverse vaccinology (RV), the first application of genomic technologies in vaccine research,
represented a major revolution in the process of discovering novel vaccines. By determining …

Cancer cells undergo major changes in energy and biosynthetic metabolism. One of them is
the Warburg effect, in which pyruvate is used for fermentation rather for oxidative …

Ovarian cancer is the most lethal gynecological cancer due to lack of clear symptom and
reliable screening biomarker in the early stage. The capability to detect the initiation of …