Pre-eclampsia: pathophysiology and clinical implications
GJ Burton, CW Redman, JM Roberts, A Moffett - Bmj, 2019 - bmj.com
Pre-eclampsia is a common disorder that particularly affects first pregnancies. The clinical
presentation is highly variable but hypertension and proteinuria are usually seen. These …
presentation is highly variable but hypertension and proteinuria are usually seen. These …
Does race or ethnicity play a role in the origin, pathophysiology, and outcomes of preeclampsia? An expert review of the literature
The burden of preeclampsia, a substantial contributor to perinatal morbidity and mortality, is
not born equally across the population. Although the prevalence of preeclampsia has been …
not born equally across the population. Although the prevalence of preeclampsia has been …
Prevalence of preeclampsia and eclampsia in adolescent pregnancy: A systematic review and meta-analysis of 291,247 adolescents worldwide since 1969
Objective Hypertensive disorders are among the main causes of maternal and perinatal
morbidity and mortality, and the findings regarding the occurrence of preeclampsia (PE) and …
morbidity and mortality, and the findings regarding the occurrence of preeclampsia (PE) and …
Prospective evaluation of cardiovascular risk 10 years after a hypertensive disorder of pregnancy
LD Levine, B Ky, JA Chirinos, J Koshinksi… - Journal of the American …, 2022 - jacc.org
Background Hypertensive disorders of pregnancy (HDP) are associated with increased risk
of cardiovascular disease (CVD) 20-30 years later; however, cardiovascular (CV) risk in the …
of cardiovascular disease (CVD) 20-30 years later; however, cardiovascular (CV) risk in the …
Review of the immune mechanisms of preeclampsia and the potential of immune modulating therapy
YC Ai-ris, LA Smith, SA Karumanchi - Human immunology, 2021 - Elsevier
Successful pregnancy relies on maternal immunologic tolerance mechanisms limit
maladaptive immune responses against the semi-allogeneic fetus and placenta and support …
maladaptive immune responses against the semi-allogeneic fetus and placenta and support …
[HTML][HTML] Two distinct molecular faces of preeclampsia revealed by single-cell transcriptomics
Introduction Preeclampsia is a multisystemic, pregnancy-specific disorder united by new-
onset hypertension but with considerable variation in clinical manifestation, onset, and …
onset hypertension but with considerable variation in clinical manifestation, onset, and …
Trace minerals, heavy metals, and preeclampsia: findings from the Boston Birth Cohort
Background Preeclampsia is a leading contributor to maternal and perinatal morbidity and
mortality. In mice experiments, manganese (Mn) and selenium (Se) are protective whereas …
mortality. In mice experiments, manganese (Mn) and selenium (Se) are protective whereas …
Hypertensive disorders of pregnancy and risk of stroke in US Black women
Background Black women have a disproportionately higher burden of both preeclamptic
pregnancy and stroke compared with White women, but virtually all existing evidence on this …
pregnancy and stroke compared with White women, but virtually all existing evidence on this …
Variations in cardiovascular structure, function, and geometry in midlife associated with a history of hypertensive pregnancy
Hypertensive pregnancy is associated with increased maternal cardiovascular risk in later
life. A range of cardiovascular adaptations after pregnancy have been reported to partly …
life. A range of cardiovascular adaptations after pregnancy have been reported to partly …
Statins in pre‐eclampsia or fetal growth restriction: A systematic review and meta‐analysis on maternal blood pressure and fetal growth across species
L Meijerink, KE Wever, F Terstappen… - … Journal of Obstetrics …, 2023 - Wiley Online Library
Background Several human randomised controlled trials (RCTs) are investigating the effects
of statins on pre‐eclampsia (PE) and fetal growth restriction (FGR). This cross‐species meta …
of statins on pre‐eclampsia (PE) and fetal growth restriction (FGR). This cross‐species meta …